Difference between revisions of "Iron metabolism"

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{{CategoryTree
 
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|Parents=
 
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* 2.6.6. [[Miscellaneous metabolic pathways]]
 
* 2.6.6. [[Miscellaneous metabolic pathways]]
 
|Related=
 
|Related=
none
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* [[Acquisition of iron]]
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* [[Fur regulon]]
 
|}}
 
|}}
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== Genes in this functional category ==
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* Note: the main systems for iron uptake in ''B. subtilis'' 168 are [[YfmF]]-[[YfmD]]-[[YfmE]]-[[YfmC]]-[[YhfQ]] and [[EfeO]]-[[EfeU]] with [[EfeB]] {{PubMed|22194458}}
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===[[ABC transporters]] for the[[Iron metabolism|uptake of iron/ siderophores]]===
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* [[YusV]]-[[FeuB]]-[[FeuC]]-[[FeuA]]: uptake of the siderophores enterobactin and bacillibactin
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* [[FhuC]]-[[FhuB]]-[[FhuG]]-[[FhuD]]-[[YxeB]]: uptake of ferrichrome und ferrioxamine
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* [[YclN]]-[[YclO]]-[[YclP]]-[[YclQ]]: uptake of petrobactin (a siderophore produced by ''B. anthracis'' and ''B. cereus'')
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* [[YusV]]-[[YfiZ]]-[[YfhA]]-[[YfiY]]: uptake of the siderophores schizokinen and arthrobactin
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* [[YfmF]]-[[YfmD]]-[[YfmE]]-[[YfmC]]-[[YhfQ]]: uptake of iron/citrate
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=== Elemental iron transport system ===
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* [[EfeO]]-[[EfeU]], [[EfeB]]
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=== Acquisition of iron/other ===
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* [[besA]]
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* [[btr]]
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* [[cypX]]
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* [[dhbA]]
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* [[dhbB]]
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* [[dhbC]]
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* [[dhbE]]
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* [[dhbF]]
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* [[dps]]
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* [[fbpA]]
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* [[fbpB]]
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* [[fbpC]]
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* [[fsrA]]
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* [[fur]]
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* [[mrgA]]
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* [[ybbA]]
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* [[yhfQ]]
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* [[ymfD]]
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* [[yvmB]]
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* [[yvmC]]
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=== Acquisition of iron/ based on similarity ===
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* [[ytoA]]
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* [[yvrA]]
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* [[yvrB]]
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* [[yvrC]]
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=== Export of Fe(II)===
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* [[pfeT]]
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=== Biosynthesis of iron-sulfur clusters ===
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* ''[[fra]]''
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* ''[[sufA]]''
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* ''[[sufB]]''
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* ''[[sufC]]''
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* ''[[sufD]]''
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* ''[[sufS]]''
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* ''[[sufU]]''
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* ''[[yitW]]''
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==Key reviews==
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<pubmed> 20467446 16211402 12732309 23192658 25160631 26259870 26488283</pubmed>
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==Important original publications ==
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<pubmed>27795321</pubmed>
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=Back to [[categories]]=

Latest revision as of 10:21, 1 November 2016

Parent categories
Neighbouring categories
Related categories

Genes in this functional category

ABC transporters for theuptake of iron/ siderophores

Elemental iron transport system

Acquisition of iron/other

Acquisition of iron/ based on similarity

Export of Fe(II)

Biosynthesis of iron-sulfur clusters

Key reviews

Erin L Mettert, Patricia J Kiley
How Is Fe-S Cluster Formation Regulated?
Annu Rev Microbiol: 2015, 69;505-26
[PubMed:26488283] [WorldCat.org] [DOI] (I p)

Zuelay Rosario-Cruz, Jeffrey M Boyd
Physiological roles of bacillithiol in intracellular metal processing.
Curr Genet: 2016, 62(1);59-65
[PubMed:26259870] [WorldCat.org] [DOI] (I p)

John D Helmann
Specificity of metal sensing: iron and manganese homeostasis in Bacillus subtilis.
J Biol Chem: 2014, 289(41);28112-20
[PubMed:25160631] [WorldCat.org] [DOI] (I p)

Marcus Miethke
Molecular strategies of microbial iron assimilation: from high-affinity complexes to cofactor assembly systems.
Metallomics: 2013, 5(1);15-28
[PubMed:23192658] [WorldCat.org] [DOI] (I p)

Béatrice Py, Frédéric Barras
Building Fe-S proteins: bacterial strategies.
Nat Rev Microbiol: 2010, 8(6);436-46
[PubMed:20467446] [WorldCat.org] [DOI] (I p)

M Fontecave, S Ollagnier de Choudens, B Py, F Barras
Mechanisms of iron-sulfur cluster assembly: the SUF machinery.
J Biol Inorg Chem: 2005, 10(7);713-21
[PubMed:16211402] [WorldCat.org] [DOI] (P p)

Patricia J Kiley, Helmut Beinert
The role of Fe-S proteins in sensing and regulation in bacteria.
Curr Opin Microbiol: 2003, 6(2);181-5
[PubMed:12732309] [WorldCat.org] [DOI] (P p)


Important original publications

Emily M Roy, Kevin L Griffith
Characterization of a Novel Iron Acquisition Activity That Coordinates the Iron Response with Population Density under Iron-Replete Conditions in Bacillus subtilis.
J Bacteriol: 2017, 199(1);
[PubMed:27795321] [WorldCat.org] [DOI] (I e)


Back to categories