Difference between revisions of "Iron metabolism"

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== Genes in this functional category ==
 
== Genes in this functional category ==
 +
* Note: the main systems for iron uptake in ''B. subtilis'' 168 are [[YfmF]]-[[YfmD]]-[[YfmE]]-[[YfmC]]-[[YhfQ]] and [[EfeO]]-[[EfeU]] with [[EfeB]] {{PubMed|22194458}}
  
==[[ABC transporters]] for the[[Iron metabolism|uptake of iron/ siderophores]]==
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===[[ABC transporters]] for the[[Iron metabolism|uptake of iron/ siderophores]]===
 
* [[YusV]]-[[FeuB]]-[[FeuC]]-[[FeuA]]: uptake of the siderophores enterobactin and bacillibactin  
 
* [[YusV]]-[[FeuB]]-[[FeuC]]-[[FeuA]]: uptake of the siderophores enterobactin and bacillibactin  
 
* [[FhuC]]-[[FhuB]]-[[FhuG]]-[[FhuD]]-[[YxeB]]: uptake of ferrichrome und ferrioxamine
 
* [[FhuC]]-[[FhuB]]-[[FhuG]]-[[FhuD]]-[[YxeB]]: uptake of ferrichrome und ferrioxamine
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* [[YfmF]]-[[YfmD]]-[[YfmE]]-[[YfmC]]-[[YhfQ]]: uptake of iron/citrate
 
* [[YfmF]]-[[YfmD]]-[[YfmE]]-[[YfmC]]-[[YhfQ]]: uptake of iron/citrate
  
== Elemental iron transport system ==
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=== Elemental iron transport system ===
 
* [[EfeO]]-[[EfeU]], [[EfeB]]
 
* [[EfeO]]-[[EfeU]], [[EfeB]]
  
== Acquisition of iron/other ==  
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=== Acquisition of iron/other ===  
 
* [[besA]]
 
* [[besA]]
 
* [[btr]]
 
* [[btr]]
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* [[fbpB]]
 
* [[fbpB]]
 
* [[fbpC]]
 
* [[fbpC]]
 
+
* [[fsrA]]
 
* [[fur]]
 
* [[fur]]
 
* [[mrgA]]
 
* [[mrgA]]
 
* [[ybbA]]
 
* [[ybbA]]
 
 
* [[yhfQ]]
 
* [[yhfQ]]
 
* [[ymfD]]
 
* [[ymfD]]
 +
* [[yvmB]]
 
* [[yvmC]]
 
* [[yvmC]]
  
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* [[yvrB]]
 
* [[yvrB]]
 
* [[yvrC]]
 
* [[yvrC]]
 +
 +
=== Export of Fe(II)===
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* [[pfeT]]
  
 
=== Biosynthesis of iron-sulfur clusters ===  
 
=== Biosynthesis of iron-sulfur clusters ===  
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* ''[[sufS]]''
 
* ''[[sufS]]''
 
* ''[[sufU]]''
 
* ''[[sufU]]''
 +
* ''[[yitW]]''
  
 
==Key reviews==
 
==Key reviews==
<pubmed> 20467446 16211402 12732309 23192658 </pubmed>
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<pubmed> 20467446 16211402 12732309 23192658 25160631 26259870 26488283</pubmed>
 +
 
 +
==Important original publications ==
 +
<pubmed>27795321</pubmed>
 +
 
 
=Back to [[categories]]=
 
=Back to [[categories]]=

Latest revision as of 10:21, 1 November 2016

Parent categories
Neighbouring categories
Related categories

Genes in this functional category

ABC transporters for theuptake of iron/ siderophores

Elemental iron transport system

Acquisition of iron/other

Acquisition of iron/ based on similarity

Export of Fe(II)

Biosynthesis of iron-sulfur clusters

Key reviews

Erin L Mettert, Patricia J Kiley
How Is Fe-S Cluster Formation Regulated?
Annu Rev Microbiol: 2015, 69;505-26
[PubMed:26488283] [WorldCat.org] [DOI] (I p)

Zuelay Rosario-Cruz, Jeffrey M Boyd
Physiological roles of bacillithiol in intracellular metal processing.
Curr Genet: 2016, 62(1);59-65
[PubMed:26259870] [WorldCat.org] [DOI] (I p)

John D Helmann
Specificity of metal sensing: iron and manganese homeostasis in Bacillus subtilis.
J Biol Chem: 2014, 289(41);28112-20
[PubMed:25160631] [WorldCat.org] [DOI] (I p)

Marcus Miethke
Molecular strategies of microbial iron assimilation: from high-affinity complexes to cofactor assembly systems.
Metallomics: 2013, 5(1);15-28
[PubMed:23192658] [WorldCat.org] [DOI] (I p)

Béatrice Py, Frédéric Barras
Building Fe-S proteins: bacterial strategies.
Nat Rev Microbiol: 2010, 8(6);436-46
[PubMed:20467446] [WorldCat.org] [DOI] (I p)

M Fontecave, S Ollagnier de Choudens, B Py, F Barras
Mechanisms of iron-sulfur cluster assembly: the SUF machinery.
J Biol Inorg Chem: 2005, 10(7);713-21
[PubMed:16211402] [WorldCat.org] [DOI] (P p)

Patricia J Kiley, Helmut Beinert
The role of Fe-S proteins in sensing and regulation in bacteria.
Curr Opin Microbiol: 2003, 6(2);181-5
[PubMed:12732309] [WorldCat.org] [DOI] (P p)


Important original publications

Emily M Roy, Kevin L Griffith
Characterization of a Novel Iron Acquisition Activity That Coordinates the Iron Response with Population Density under Iron-Replete Conditions in Bacillus subtilis.
J Bacteriol: 2017, 199(1);
[PubMed:27795321] [WorldCat.org] [DOI] (I e)


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