LytS

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  • Description: two-component sensor kinase, regulation of rate of autolysis

Gene name lytS
Synonyms
Essential no
Product two-component sensor kinase
Function regulation of the rate of autolysis
Interactions involving this protein in SubtInteract: LytS
MW, pI 64 kDa, 8.241
Gene length, protein length 1779 bp, 593 aa
Immediate neighbours lytT, ysaA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
LytS context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

cell wall degradation/ turnover, protein modification, transcription factors and their control, membrane proteins, phosphoproteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU28930

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: ATP + LytT = ADP + LytT-P
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains: 5 transmembrane regions
  • Modification: autophosphorylation on a His residue
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization: membrane (putative, due to presence of 5 membrane-spanning domains)

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

C Fabret, V A Feher, J A Hoch
Two-component signal transduction in Bacillus subtilis: how one organism sees its world.
J Bacteriol: 1999, 181(7);1975-83
[PubMed:10094672] [WorldCat.org] [DOI] (P p)