LytS

• Description: two-component sensor kinase, regulation of rate of autolysis
  
  

Gene name	lytS
Synonyms
Essential	no
Product	two-component sensor kinase
Function	regulation of the rate of autolysis
Gene expression levels in SubtiExpress: lytS
Interactions involving this protein in SubtInteract: LytS
MW, pI	64 kDa, 8.241
Gene length, protein length	1779 bp, 593 aa
Immediate neighbours	lytT, ysaA
Sequences	Protein DNA Advanced_DNA
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

cell wall degradation/ turnover, protein modification, transcription factors and their control, membrane proteins, phosphoproteins

The gene

Basic information

• Locus tag: BSU28930

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: ATP + LytT = ADP + LytT-P

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains: 5 transmembrane regions

• Modification: autophosphorylation on a His residue

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • LytT-LytS

• Localization: membrane (putative, due to presence of 5 membrane-spanning domains)

Database entries

• Structure:

• UniProt: P94513

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: lytS PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

C Fabret, V A Feher, J A Hoch
Two-component signal transduction in Bacillus subtilis: how one organism sees its world.
J Bacteriol: 1999, 181(7);1975-83
[PubMed:10094672] [WorldCat.org] [DOI] (P p)