LytS

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  • Description: two-component sensor kinase, regulation of rate of autolysis

Gene name lytS
Synonyms
Essential no
Product two-component sensor kinase
Function regulation of the rate of autolysis
Gene expression levels in SubtiExpress: lytS
Interactions involving this protein in SubtInteract: LytS
MW, pI 64 kDa, 8.241
Gene length, protein length 1779 bp, 593 aa
Immediate neighbours lytT, ysaA
Sequences Protein DNA DNA_with_flanks
Genetic context
LytS context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
LytS expression.png
























Categories containing this gene/protein

cell wall degradation/ turnover, protein modification, transcription factors and their control, membrane proteins, phosphoproteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU28930

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: ATP + LytT = ADP + LytT-P
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains: 5 transmembrane regions
  • Modification: autophosphorylation on a His residue
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization: membrane (putative, due to presence of 5 membrane-spanning domains)

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

C Fabret, V A Feher, J A Hoch
Two-component signal transduction in Bacillus subtilis: how one organism sees its world.
J Bacteriol: 1999, 181(7);1975-83
[PubMed:10094672] [WorldCat.org] [DOI] (P p)