NonA

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  • Description: confers resistance to infection with phage SP10

Gene name nonA
Synonyms
Essential no
Product inhibitor of NrdEF of phage SP10
Function protection against phage SP10
Gene expression levels in SubtiExpress: nonA
MW, pI 8,465 kDa, 9.64
Gene length, protein length 219 bp, 72 aa
Immediate neighbours yosP, nrdEB
Genetic context
YosP context.gif
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Categories containing this gene/protein

SP-beta prophage, membrane proteins


This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: none

Phenotypes of a mutant

  • overexpression interferes with respiration (likely due to inhibition of NrdE) PubMed

Database entries

  • BsubCyc: no entry
  • DBTBS entry: no entry
  • SubtiList entry: no entry

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • BsubCyc: no entry
  • Structure:
  • UniProt: no entry
  • KEGG entry: no entry
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed at late stage of phage SP10 infection PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Tatsuya Yamamoto, Nozomu Obana, Lii Mien Yee, Kei Asai, Nobuhiko Nomura, Kouji Nakamura
SP10 infectivity is aborted after bacteriophage SP10 infection induces nonA transcription on the prophage SPβ region of the Bacillus subtilis genome.
J Bacteriol: 2014, 196(3);693-706
[PubMed:24272782] [WorldCat.org] [DOI] (I p)