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=Tuesday April 24th 2012 – Morning=
 
  
* 8:00-8:45 - REGISTRATION
+
= Tuesday 12th June =
* 9:00-9:10 – Welcome Introduction [[Kevin Devine]]
 
  
==Session I: Modeling and Networks ==                                                                                                                 
+
* 8:30 – 8:55 Registration
CHAIR: [[Sierd Bron]]
+
* 8:55 Welcome - Chancellors’ Building, room 1.12
 
* 9:10-9:30 – BACELL Systems – Past, Present, Future
 
** [[Jan Maarten van Dijl]] (University Medical Center Groningen)
 
  
* 9:30-9:50 – Unraveling the [[ncRNA|Small Regulatory RNA]] Network of ''Bacillus subtilis''  
+
== Session 1 Regulation==
** Ruben Mars (University Medical Center Groningen)
+
CHAIR:  David Leak
 +
* 09:00 [[Ciaran Condon]]
 +
** Suppression of the essential nature of RNase M16 ([[YqfG]]), required for 3' maturation of ''B. subtilis'' 16S ribosomal RNA, by deletion of [[rnr|RNase R]]
 +
* 09:15 [[Roland Hartmann]]
 +
** Function and regulation of two 6S RNAs in Bacillus subtilis
 +
* 09:30 [[Matthias Mack]]
 +
** A dual control mechanism synchronizes riboflavin and sulphur metabolism in ''Bacillus subtilis''
 +
* 09:45 Hermann Rath
 +
** A [[SigB]]-dependent antisense RNA affects osmotic induction of ''[[opuBA|opuB]]'' expression in ''Bacillus subtilis''
 +
* 10:00 Laura Teichmann
 +
** Suppressor analysis illuminates the structure/function relationship of the glycine betaine synthesis repressor [[GbsR]]
 +
* 10:15 Sylvain Durand
 +
** sRNA-mediated activation of gene expression by inhibition of 5’-3’exonucleolytic mRNA degradation
  
* 9:50-10:10 A Computational [[Stressosome]] Model Consolidates Hypotheses about Environmental Activation of [[SigB]] the General Stress response
+
== 10:30 11:00 Tea and Coffee - Chancellors’ Building, ground floor foyer==
** Ulf Liebal (University of Rostock)
 
  
* 10:10-10:30 – Reconciling Molecular Regulatory Mechanisms with Noise Patterns of Bacterial Metabolic Promoters in Induced and Repressed States
+
== Session 2 [[Cell division]]==
** Matthieu Jules (Institut Micalis, INRA)
+
CHAIR:  TBA
 +
* 11:00 [[Henrik Strahl]]
 +
** ''Bacillus subtilis'' does not form microscopically detectable cardiolipin domains
 +
* 11:15 Jeanine Rismondo
 +
** Discovery of genes required for lipoteichoic acid glycosylation predicts two distinct mechanism for wall teichoic acid glycosylation
 +
* 11:30 Edward de Koning
 +
** [[Divisome]] maturation in ''Bacillus subtilis'' single cells
 +
* 11:45 Seamus Holden
 +
** Treadmilling by [[FtsZ]] filaments drives ''Bacillus subtilis'' [[cell wall synthesis|peptidoglycan synthesis]] and bacterial [[cell division]]
 +
* 12:00 [[Dirk-Jan Scheffers]]
 +
** [[PbpB|PBP2B]] [[PASTA domains]] interact with [[DivIB]] to stabilize [[cell division]]
 +
* 12:15 Yongqiang Gao
 +
** [[Cell division]] in the cell wall-less bacterium ''Acholeplasma laidlawii''
  
* 10:30 – 11:00 – COFFEE BREAK
 
  
== Session II: [[Cell wall degradation/ turnover|Cell Wall]] ==
+
== 12:30 – 14:30 Lunch and Poster Session 1==
CHAIR: [[Colin Harwood]]
 
  
* 11:00-11:20 – The [[WalR]]/[[WalK]], [[PhoP]]/[[PhoR]] and [[SigI]]/[[RsgI]] Regulatory Systems of ''Bacillus subtilis'' Cooperate to Control Cell Wall Metabolism during Growth and Under Stress Conditions
+
== Session 3 – Interesting Biology ==
** Letal Salzberg (Trinity College Dublin)
+
CHAIR: [[Colin Harwood]]
 +
* 14:30 [[Jörg Stülke]]  
 +
** DNA topoisomerases in ''Bacillus subtilis'': A tale on mutants and suppressors
 +
* 14:45 Hannah Gaimster
 +
** Lethal depletion of essential cell envelope proteins can be rescued by slowing [[DNA replication]] in ''Bacillus subtilis''
 +
* 15:00 Alexandre Deloupy
 +
** Stochastic gene expression in Bacillus subtilis
 +
* 15:15 Sabine Schneider
 +
** Development of a reporter gene system to characterise [[riboswitch]] function and to identify [[riboswitch]] modulators by high-throughput screening
 +
* 15:30 [[Ken-ichi Yoshida]]  
 +
** Rapid conjugative mobilization of a 100 kb segment of ''Bacillus subtilis'' chromosomal DNA is mediated by a helper plasmid with no ability for self-transfer
 +
* 15:45 Anna A. Toymentseva
 +
** Mobilization and transfer of plasmids and chromosomal DNA mediated by optimized ICEBs1 conjugative element
  
* 11:20-11:40 Adaptation of ''Bacillus subtilis'' to High Salinity: Osmotic Induction of the Cell Wall Hydrolase [[YqiI]]
+
==16:00 16:30 Tea and Coffee ==
** Kathleen Fischer (Philipps-Universität Marburg)
+
 
+
==Session 4 – Antibiotics 1 ==
* 11:40-12:00 – Regulatory and Cellular Dynamics of the Lia-Response of ''Bacillus subtilis''
+
CHAIR: [[Ulrike Mäder]]
** [[Thorsten Mascher]] (Ludwig-Maximilians-University Munich)
+
* 16:30 Carolin Kobras
 
+
** Exploring the substrate specificity of the antimicrobial peptide resistance transporter [[BceA]]-[[BceB]] in ''Bacillus subtilis''  
* 12:00-12:20 – [[SepF]] is a New Membrane Anchor for the Key [[Cell Division]] Protein [[FtsZ]]
+
* 16:45 Luiza P. Morawska
** Ilkay Celik (Newcastle University)
+
** Preadaptation of ''Bacillus subtilis'' to mild osmostress contributes to increased antibiotic resistance
 
+
* 17:00 Mary K. Phillips-Jones
* 12:20-12:40 – The Bacterial [[MreB]] Cytoskeleton Organizes the Cell Membrane
+
** Characterisation of the VanA-type VanS histidine kinase involved in glycopeptide resistance in Gram-positive bacteria and its ligand interactions
** Henrik Strahl (Newcastle University)
+
* 17:15 Gabriela Henriques
 
+
** Towards the understanding of the regulation of [[SppA]] by [[YteJ]] in Bacillus subtilis.
* 12:40 – 14:20 LUNCH (+ BACIP MEETING)
 
 
 
=Tuesday April 24th 2012 – Afternoon=
 
 
 
== Session III: Adaptation, [[Sporulation]] and [[DNA replication|DNA Replication]] ==
 
CHAIR: [[Ulrike Mäder]]
 
 
 
* 14:20-14:40 – Selecting Better Bet Hedging ''Bacillus'' Strains
 
** Jeroen Siebring (University of Groningen)
 
 
 
* 14:40-15:00 – Spore Coat Proteins: Self-Assembly Properties and Protein-Protein [[SubtInteract|Interactions]]
 
** Daniela Krajčíková (Slovak Academy of Sciences)
 
 
 
* 15:00-15:20 – [[Spo0A]] links [[DNA replication|DNA Replication]] with [[Sporulation]] by Direct Binding to the Origin of Replication in ''Bacillus subtilis''  
 
** Mirjam Boonstra (University of Groningen)
 
 
 
** 15:20-15:40 – DSB Repair Pathway is Required for Viability of the [[smc|SMC]]-[[ScpA]]-[[ScpB]] Depleted Strain
 
** Etienne Dervyn (Institut Micalis, INRA)
 
 
 
* 15:40-16:10 - COFFEE BREAK
 
 
 
== Session IV: Antibiotics ==
 
CHAIR: [[Eugenio Ferrari]]
 
 
 
* 16:10-16:30 – Regulated Expression of a Multidrug-[[ABC transporters|ABC Transporter]] – The ''[[yheH]]-[[yheI]]-[[yheJ]]'' Operon
 
** Ewoud Reilman (University of Groningen)
 
 
 
* 16:30-16:50 – Signal Transduction in Antimicrobial Peptide Detoxification Modules of ''Bacillus subtilis'': Interaction between [[ABC transporters|ABC Transport]] and Sensor Kinase
 
** Susanne Gebhard (Ludwig-Maximilians-University Munich)
 
 
 
* 16:50-17:10 – Structure-Function Relationship of the Lantibiotic Immunity-Protein SpaI
 
** Sophie Bochmann (Goethe University Frankfurt)
 
 
 
* 17:10-17:30 – Structure, Biosynthesis and Properties of Kurstakins, Nonribosomal Lipopeptides from ''Bacillus'' spp.
 
** Philippe Jacques (Universite de Lille)
 
 
 
== 17.30-18.30 BACELL STEERING GROUP MEETING ==
 
== 19:30 – WINE RECEPTION ==
 
== 20:00 - DINNER ==
 
 
 
= Wednesday April 25th 2012 - Morning =
 
== Session V: Application ==
 
CHAIR: [[Jörg Stülke]]
 
 
 
* 9:00-9:20 – ''Bacillus subtilis'' Cell Factory Producing Scyllo-Inositol, A Potential Therapeutic Agent for Alzheimer’s Disease
 
** [[Ken-ichi Yoshida]] (Kobe University)
 
 
 
* 9:20-9:40 – Developing an Enzyme Discovery Tool for ''Bacillus subtilis''
 
** Tjeerd van Rij (DSM)
 
 
 
* 9:40 – 10:00 - Use of ''Bacillus amyloliquefaciens'' for Control of Plant Stress
 
** Johan Meijer (University of Uppsala)
 
 
 
* 10:00 – 10:20 – Phenotypic Heterogeneity during Heterologous Protein Production in ''Bacillus megaterium''
 
** Rebekka Biedendieck (Technische Universität Braunschweig)
 
 
 
* 10:20-10:40 – Absolute Protein Quantification - Application in ''Bacillus subtilis''
 
** [[Dörte Becher]] (Ernst-Moritz-Arndt Universität Greifswald)
 
  
10:40-11:00  - COFFEE BREAK
+
== Free evening in Bath ==
  
== Session VI: RNA Metabolism and Regulation ==
+
= Wednesday 13th June =
CHAIR: [[Uwe Völker]]
 
  
* 11:00-11:20 – Three Essential Ribonucleases [[rny|RNase Y]], [[rnjA|J1]] and [[rnc|III]] Control the Abundance of a Majority of ''B. subtilis'' mRNAs
+
== Session 5 Biotechnology ==
** [[Ciaran Condon|Ciarán Condon]] (Institut de Biologie Physico-Chimique CNRS)
+
CHAIR:  Anne Breüner
 +
* 9:00 Andreas Knapp
 +
** The spacer region in the 5´-UTR strongly affects recombinant protein production in ''Bacillus subtilis''
 +
* 9:15 Alexandria Holland
 +
** Investigating protein secretion in ''Geobacillus thermoglucosidasius''
 +
* 9:30 Matthew Styles
 +
** Engineering ''Parageobacillus'' for the Production of Terpenes: Building Better Chassis Organisms for Industrial Biotechnology
 +
* 9:45 Luca Longanesi
 +
** γ-PGA production through Consolidated Bioprocessing in engineered ''B. subtilis'' lab strains
 +
* 10:00 Matteo Cavaletti
 +
** Optimization of γ-PGA biosynthesis supported by synthetic biology and metabolic engineering strategies
 +
* 10:15 Ioannis Mougiakos
 +
** Characterizing a thermostable Cas9 for bacterial genome editing and silencing
  
* 11:20-11:40 – The Effects of [[RpoE]] and [[HelD]] on [[RNA polymerase|RNA Polymerase]] from ''Bacillus subtilis''
+
== 10:15 - 10:45 Tea and Coffee ==
** [[Libor Krasny|Libor Krásný]] (Academy of Sciences of the Czech Republic)
 
  
* 11:40 – 12:00 – Dynamic Localization of an [[LicT|RNA-Binding Transcription Factor]] in ''Bacillus subtilis''  
+
== Session 6 - [[Sporulation]] and development ==
** Fabian Rothe (University of Göttingen)
+
CHAIR:  TBC
 +
* 10:45 [[Imrich Barák]]
 +
** What we (don’t) know about the asymmetric septum in ''Bacillus subtilis''
 +
* 11:00 Munehiro Asally
 +
** Quality monitoring during [[sporulation]] in ''B. subtilis''
 +
* 11:15 [[Ilka Bischofs]]
 +
** Phenotypic memory links different stages of the ''B. subtilis'' life cycle
 +
* 11:30 [[Akos Kovacs]]
 +
** Cheating promotes evolution of hyper-cooperators by shifting phenotypic heterogeneity in biofilms
 +
* 11:45 [[Sven Halbedel]]
 +
** Novel ''[[gpsB]]'' suppressor genes contributing to regulatory proteolysis and ''cell division''
 +
* 12:00 Sofia Arnaouteli
 +
** Exploring the role of pulcherrimin in ''Bacillus subtilis'' [[biofilm formation]]
 +
* 12:15 Karin Bjerre
 +
** Investigating of ''Bacillus subtilis'' and ''Bacillus amyloliquefaciens'' spores and vegetative cells in fecal samples from pigs
  
* 12:00 12:20 – Requirements for the High-Frequency Activation of the Cryptic ''[[gudB]]'' Glutamate Dehydrogenase Gene in ''Bacillus subtilis''
+
==12:30 14:30 Lunch and Poster Session 2 ==
** Fabian Commichau (Georg-August-Universität Göttingen)
 
  
* 12:20-12:40 – The Anaerobic Formation of Acetoin Regulated by the Transcriptional Regulator [[AlsR]] – Part of [[pH homeostasis|pH Homeostasis]] in ''Bacillus subtilis''  
+
==Session 7 – Antibiotics 2 ==
** [[Elisabeth Härtig]] (TU Braunschweig)
+
CHAIR:  [[Kevin Devine]]
 +
* 14:30 Auke J. van Heel
 +
** BAGEL4: A user-friendly web server to mine RiPPs and bacteriocins
 +
* 14:45 Amanda Y. van Tilburg
 +
** ''Bacillus subtilis'' as heterologous production host for lantibiotics
 +
* 15:00 Nina Lautenschlaeger
 +
** A novel heterologous whole-cell biosensor in ''Bacillus subtilis'' for the comprehensive detection of b-lactam antibiotics
 +
* 15:15 Marjorie Gibbon
 +
** Towards understanding signalling between the bacitracin resistance transporter [[BceA]]-[[BceB]] and histidine kinase [[BceS]] of ''Bacillus subtilis''
  
12:40-14:00 – LUNCH
+
== 15:30 – 16:00 Tea and Coffee ==
  
= Wednesday April 25th 2012 - Afternoon=
+
== Session 8 – Cereus Group ==
== EU BaSynthec Synthetic Biology Symposium ==
+
CHAIR: [[Cinzia Calvio]]
CHAIR: [[Kevin Devine]]
+
* 16:00 Monika Ehling-Schulz
 +
** ''Bacillus cereus'', a multifaceted pathogen: The challenge of discriminating high and low enteropathogenic strains
 +
* 16:15 Nick Waterfield
 +
** ''Bacillus cereus'' G9241 – to anthrax and back again
 +
* 16:30 Ludivine Rousset
 +
** Oligotrophy induces phenotypic diversification of ''Bacillus cereus'' AH187
 +
* 16:45 Jan Maarten van Dijl
 +
** Can ''Bacillus thuringiensis'' and other microorganisms isolated from chronic wounds ‘pacify’ ''Staphylococcus aureus''?
  
* 14:00-14:10 – Introduction – [[Philippe Noirot]] (INRA)
+
== 17:00 Closing Remarks==
* 14:10-14:40 – Enhanced Recombinant Protein Productivity by Genome Reduction in ''Bacillus subtilis'' - [[Naotake Ogasawara]] (Nara Institute)
 
* 14:40-15:10 – Computational and Bioinformatics Approaches to Enabling Synthetic Biology - Anil Wipat (Newcastle University)
 
* 15:10-15:40 – Highly Modified Peptides by Synthetic Biology Approaches - [[Oscar Kuipers]] (Groningen University)
 
  
* 15:40-16:10 COFFEE BREAK
+
== 19:00 – 23:00 Social event at The Terrace, The Roman Baths, generously supported by BACIP to include the prize giving for best posters and talks from PhD/Postdocs ==
  
* 16:10-16:40 – ''Bacillus subtilis'' Minimal Genome Work in Europe - [[Philippe Noirot]] (INRA)
 
* 16:40-17:10 – View of Novozymes on Synthetic Biology - Allen Kent Nielsen (Novozymes)
 
* 17:10-17:40 – View of DSM on Synthetic Biology - [[Zoltan Pragai|Zoltán Prágai]] (DSM)
 
* 17:40-17:50 – Wrap up / end of workshop – [[Philippe Noirot]] (INRA)
 
  
 +
= END OF MEETING =
  
  
 
=Back to [[Main Page|SubtiWiki]]=
 
=Back to [[Main Page|SubtiWiki]]=

Latest revision as of 15:38, 4 June 2018

Tuesday 12th June

  • 8:30 – 8:55 Registration
  • 8:55 Welcome - Chancellors’ Building, room 1.12

Session 1 Regulation

CHAIR: David Leak

  • 09:00 Ciaran Condon
    • Suppression of the essential nature of RNase M16 (YqfG), required for 3' maturation of B. subtilis 16S ribosomal RNA, by deletion of RNase R
  • 09:15 Roland Hartmann
    • Function and regulation of two 6S RNAs in Bacillus subtilis
  • 09:30 Matthias Mack
    • A dual control mechanism synchronizes riboflavin and sulphur metabolism in Bacillus subtilis
  • 09:45 Hermann Rath
    • A SigB-dependent antisense RNA affects osmotic induction of opuB expression in Bacillus subtilis
  • 10:00 Laura Teichmann
    • Suppressor analysis illuminates the structure/function relationship of the glycine betaine synthesis repressor GbsR
  • 10:15 Sylvain Durand
    • sRNA-mediated activation of gene expression by inhibition of 5’-3’exonucleolytic mRNA degradation

10:30 – 11:00 Tea and Coffee - Chancellors’ Building, ground floor foyer

Session 2 Cell division

CHAIR: TBA

  • 11:00 Henrik Strahl
    • Bacillus subtilis does not form microscopically detectable cardiolipin domains
  • 11:15 Jeanine Rismondo
    • Discovery of genes required for lipoteichoic acid glycosylation predicts two distinct mechanism for wall teichoic acid glycosylation
  • 11:30 Edward de Koning
    • Divisome maturation in Bacillus subtilis single cells
  • 11:45 Seamus Holden
  • 12:00 Dirk-Jan Scheffers
  • 12:15 Yongqiang Gao
    • Cell division in the cell wall-less bacterium Acholeplasma laidlawii


12:30 – 14:30 Lunch and Poster Session 1

Session 3 – Interesting Biology

CHAIR: Colin Harwood

  • 14:30 Jörg Stülke
    • DNA topoisomerases in Bacillus subtilis: A tale on mutants and suppressors
  • 14:45 Hannah Gaimster
    • Lethal depletion of essential cell envelope proteins can be rescued by slowing DNA replication in Bacillus subtilis
  • 15:00 Alexandre Deloupy
    • Stochastic gene expression in Bacillus subtilis
  • 15:15 Sabine Schneider
    • Development of a reporter gene system to characterise riboswitch function and to identify riboswitch modulators by high-throughput screening
  • 15:30 Ken-ichi Yoshida
    • Rapid conjugative mobilization of a 100 kb segment of Bacillus subtilis chromosomal DNA is mediated by a helper plasmid with no ability for self-transfer
  • 15:45 Anna A. Toymentseva
    • Mobilization and transfer of plasmids and chromosomal DNA mediated by optimized ICEBs1 conjugative element

16:00 – 16:30 Tea and Coffee

Session 4 – Antibiotics 1

CHAIR: Ulrike Mäder

  • 16:30 Carolin Kobras
    • Exploring the substrate specificity of the antimicrobial peptide resistance transporter BceA-BceB in Bacillus subtilis
  • 16:45 Luiza P. Morawska
    • Preadaptation of Bacillus subtilis to mild osmostress contributes to increased antibiotic resistance
  • 17:00 Mary K. Phillips-Jones
    • Characterisation of the VanA-type VanS histidine kinase involved in glycopeptide resistance in Gram-positive bacteria and its ligand interactions
  • 17:15 Gabriela Henriques
    • Towards the understanding of the regulation of SppA by YteJ in Bacillus subtilis.

Free evening in Bath

Wednesday 13th June

Session 5 Biotechnology

CHAIR: Anne Breüner

  • 9:00 Andreas Knapp
    • The spacer region in the 5´-UTR strongly affects recombinant protein production in Bacillus subtilis
  • 9:15 Alexandria Holland
    • Investigating protein secretion in Geobacillus thermoglucosidasius
  • 9:30 Matthew Styles
    • Engineering Parageobacillus for the Production of Terpenes: Building Better Chassis Organisms for Industrial Biotechnology
  • 9:45 Luca Longanesi
    • γ-PGA production through Consolidated Bioprocessing in engineered B. subtilis lab strains
  • 10:00 Matteo Cavaletti
    • Optimization of γ-PGA biosynthesis supported by synthetic biology and metabolic engineering strategies
  • 10:15 Ioannis Mougiakos
    • Characterizing a thermostable Cas9 for bacterial genome editing and silencing

10:15 - 10:45 Tea and Coffee

Session 6 - Sporulation and development

CHAIR: TBC

  • 10:45 Imrich Barák
    • What we (don’t) know about the asymmetric septum in Bacillus subtilis
  • 11:00 Munehiro Asally
  • 11:15 Ilka Bischofs
    • Phenotypic memory links different stages of the B. subtilis life cycle
  • 11:30 Akos Kovacs
    • Cheating promotes evolution of hyper-cooperators by shifting phenotypic heterogeneity in biofilms
  • 11:45 Sven Halbedel
    • Novel gpsB suppressor genes contributing to regulatory proteolysis and cell division
  • 12:00 Sofia Arnaouteli
  • 12:15 Karin Bjerre
    • Investigating of Bacillus subtilis and Bacillus amyloliquefaciens spores and vegetative cells in fecal samples from pigs

12:30 – 14:30 Lunch and Poster Session 2

Session 7 – Antibiotics 2

CHAIR: Kevin Devine

  • 14:30 Auke J. van Heel
    • BAGEL4: A user-friendly web server to mine RiPPs and bacteriocins
  • 14:45 Amanda Y. van Tilburg
    • Bacillus subtilis as heterologous production host for lantibiotics
  • 15:00 Nina Lautenschlaeger
    • A novel heterologous whole-cell biosensor in Bacillus subtilis for the comprehensive detection of b-lactam antibiotics
  • 15:15 Marjorie Gibbon
    • Towards understanding signalling between the bacitracin resistance transporter BceA-BceB and histidine kinase BceS of Bacillus subtilis

15:30 – 16:00 Tea and Coffee

Session 8 – Cereus Group

CHAIR: Cinzia Calvio

  • 16:00 Monika Ehling-Schulz
    • Bacillus cereus, a multifaceted pathogen: The challenge of discriminating high and low enteropathogenic strains
  • 16:15 Nick Waterfield
    • Bacillus cereus G9241 – to anthrax and back again
  • 16:30 Ludivine Rousset
    • Oligotrophy induces phenotypic diversification of Bacillus cereus AH187
  • 16:45 Jan Maarten van Dijl
    • Can Bacillus thuringiensis and other microorganisms isolated from chronic wounds ‘pacify’ Staphylococcus aureus?

17:00 Closing Remarks

19:00 – 23:00 Social event at The Terrace, The Roman Baths, generously supported by BACIP – to include the prize giving for best posters and talks from PhD/Postdocs

END OF MEETING

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