Difference between revisions of "Program"

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= Monday June 22, 2015 =
 
  
* 8:15 - 8:30 – Welcome remarks, [[Jim Hoch]], [[Marta Perego]]
+
= Tuesday 12th June =
* 8:30 - 9:15 - Keynote lecture: Andrew Camilli, Boston, USA
 
** The ''Streptococcus pneumoniae'' cell wall controls pneumolysin release and contributes to virulence.
 
== Session I Signal transduction I==
 
CHAIR:  [[Marta Perego]]
 
* 9:15 - 9:30 – [[Kevin Devine]], Dublin, Ireland
 
** The activities of the [[WalR]]-[[WalK]] and [[PhoP]]-[[PhoR]] [[two-component systems|two-component signal transduction systems]] are determined by signals that emanate from cell wall metabolism in ''Bacillus subtilis''
 
* 9:30 - 9:45 – [[Hendrik Szurmant]], La Jolla. USA
 
** The [[YycF]]-[[YycG]] [[two-component systems|two-component system]] as a regulatory feedback loop for the expression of autolysin activity and the target of antimicrobial activities by human chemokines.
 
* 9:45 - 10:00 – [[Tarek Msadek]], Paris, France
 
** Peptide antibiotic resistance and intramembrane kinase signaling in ''Staphylococcus aureus''.
 
  
* 10:00 10:30 – COFFEE BREAK
+
* 8:30 8:55 Registration
 +
* 8:55 Welcome - Chancellors’ Building, room 1.12
  
== Session II Signal transduction II ==
+
== Session 1 Regulation==
CHAIR: [[Kevin Devine]]
+
CHAIR: David Leak
* 10:30 - 10:45 – Mary K. Phillips-Jones, Preston, UK
+
* 09:00 [[Ciaran Condon]]  
** Characterization of ligand binding by VanS, the membrane sensor kinase of the [[two-component systems|two-component system]] regulating A-type vancomycin resistance in the enterococci.
+
** Suppression of the essential nature of RNase M16 ([[YqfG]]), required for 3' maturation of ''B. subtilis'' 16S ribosomal RNA, by deletion of [[rnr|RNase R]]
* 10:45 - 11:00 – Emanuel Hanski, Jerusalem, Israel
+
* 09:15 [[Roland Hartmann]]
** Regulation of group A ''Streptococcus'' virulence by sensing of asparagines.
+
** Function and regulation of two 6S RNAs in Bacillus subtilis
* 11:00 - 11:15 – Nicola Horstmann, Houston, USA
+
* 09:30 [[Matthias Mack]]
** Regulation of dual-site phosphorylation of response regulator CovR and its impact on group A streptococcus global gene expression and virulence.
+
** A dual control mechanism synchronizes riboflavin and sulphur metabolism in ''Bacillus subtilis''
* 11:15 - 11:30 – Andrew Ulijasz, London, UK
+
* 09:45 Hermann Rath
** A novel family of [[two-component systems|two-component like]] redox sensors in the Streptococci.
+
** A [[SigB]]-dependent antisense RNA affects osmotic induction of ''[[opuBA|opuB]]'' expression in ''Bacillus subtilis''
* 11:30 - 11:45 – [[Marta Perego]], La Jolla, USA
+
* 10:00 Laura Teichmann
** Media-dependent regulation of ''Bacillus anthracis'' toxin gene expression by the [[ResD]]-[[ResE]]-controlled respiration pathway.
+
** Suppressor analysis illuminates the structure/function relationship of the glycine betaine synthesis repressor [[GbsR]]
* 11:45 - 12:00 – Maria Cecilia Manilla, Rosario, Argentina
+
* 10:15 Sylvain Durand
** Proline residues of [[DesK]] as transmitting elements of cold stimulus.
+
** sRNA-mediated activation of gene expression by inhibition of 5’-3’exonucleolytic mRNA degradation
* 12:00 - 12:15 – [[Ken-ichi Yoshida]], Kobe, Japan
 
** Hyperphosphorylation of [[DegU]] interferes with [[CcpA]]-dependent catabolite repression of ''[[rocG]]'' in ''Bacillus subtilis''.
 
  
* 12:30 – 14:00 LUNCH
+
== 10:30 – 11:00 Tea and Coffee - Chancellors’ Building, ground floor foyer==
  
== Session III Industrial Research ==
+
== Session 2 [[Cell division]]==
CHAIR:  Ghislain Schyns
+
CHAIR:  TBA
* 14:00 - 14:45 – Keynote lecture: Sven Panke, Zürich, Switzerland
+
* 11:00 [[Henrik Strahl]]
** tba
+
** ''Bacillus subtilis'' does not form microscopically detectable cardiolipin domains
* 14:45 - 15:00 – Abderahmane Derouiche, Gothenburg, Sweden
+
* 11:15 Jeanine Rismondo
** ''Bacillus subtilis'' [[SalA]] is a phosphorylation-dependent transcription factor that regulates the production of the exoprotease [[AprE]].
+
** Discovery of genes required for lipoteichoic acid glycosylation predicts two distinct mechanism for wall teichoic acid glycosylation
* 15:00 - 15:15 –Jolanda Neef, Groningen, Netherlands
+
* 11:30 Edward de Koning
** A novel expression platform for the production of cell wall-bound and secreted staphylococcal antigens.
+
** [[Divisome]] maturation in ''Bacillus subtilis'' single cells
* 15:15 - 15:30 – Ferro Iolanda, Potsdam, Germany
+
* 11:45 Seamus Holden
** tRNA abundance and aminoacylation in ''Bacillus licheniformis''.
+
** Treadmilling by [[FtsZ]] filaments drives ''Bacillus subtilis'' [[cell wall synthesis|peptidoglycan synthesis]] and bacterial [[cell division]]
* 15:30 - 15:45 –Birgit Voigt, Greifswald, Germany
+
* 12:00 [[Dirk-Jan Scheffers]]
** The response of ''Bacillus pumilus'' to hydrogen peroxide-provoked oxidative stress.
+
** [[PbpB|PBP2B]] [[PASTA domains]] interact with [[DivIB]] to stabilize [[cell division]]
 +
* 12:15 Yongqiang Gao
 +
** [[Cell division]] in the cell wall-less bacterium ''Acholeplasma laidlawii''
  
* 15:45 - 16:15 - COFFEE BREAK
 
  
== Session IV: Vaccines ==
+
== 12:30 – 14:30 Lunch and Poster Session 1==
CHAIR: Guido Grandi
 
* 16:15 - 16:30 – Fabio Bagnoi, Siena, Italy
 
** Vaccine composition formulated with a novel TLR7-dependent adjuvant induces high and broad protection against ''Staphylococcus aureus''.
 
* 16:30 - 16:45 – Olaf Schneewind, Chicago, USA
 
** Protein A suppresses immune responses during ''Staphylococcus aureus'' bloodstream infection in guinea pigs.
 
* 16:45 - 17:00 – Johannes Hübner, Munich, Germany
 
** Towards a vaccine against enterococci: Reverse vaccinology and beyond.
 
* 17:00 - 17:15– Edmondo Campisi, Siena, Italy
 
** Structural and genetic characterization of the Type IX Group B ''Streptococcus'' capsular polysaccharide and its relationship with types V and VII
 
* 17:15 - 17:30 – Joseph J. Zeppa, London, Ontario, Canada
 
** Vaccine approaches targeting colonization by ''Streptococcus pyogenes''.
 
  
== 17.30 - 19.30 Poster Session I==
+
== Session 3 – Interesting Biology ==
 +
CHAIR:  [[Colin Harwood]]
 +
* 14:30 [[Jörg Stülke]]
 +
** DNA topoisomerases in ''Bacillus subtilis'': A tale on mutants and suppressors
 +
* 14:45 Hannah Gaimster
 +
** Lethal depletion of essential cell envelope proteins can be rescued by slowing [[DNA replication]] in ''Bacillus subtilis''
 +
* 15:00 Alexandre Deloupy
 +
** Stochastic gene expression in Bacillus subtilis
 +
* 15:15 Sabine Schneider
 +
** Development of a reporter gene system to characterise [[riboswitch]] function and to identify [[riboswitch]] modulators by high-throughput screening
 +
* 15:30 [[Ken-ichi Yoshida]]
 +
** Rapid conjugative mobilization of a 100 kb segment of ''Bacillus subtilis'' chromosomal DNA is mediated by a helper plasmid with no ability for self-transfer
 +
* 15:45 Anna A. Toymentseva
 +
** Mobilization and transfer of plasmids and chromosomal DNA mediated by optimized ICEBs1 conjugative element
  
= Wednesday April 15th 2015 =
+
==16:00 – 16:30 Tea and Coffee ==
== Session V: Tools et al. ==
+
CHAIR: [[Stephane Aymerich]]
+
==Session 4 – Antibiotics 1 ==
* 9:00 - 9:15 – Jara Radeck, Munich, DE
+
CHAIR: [[Ulrike Mäder]]
** The ''Bacillus'' BioBrick Box 2.0: Generation and Evaluation of New Essential Genetic Building Blocks for Standardized Work with ''Bacillus subtilis''
+
* 16:30 Carolin Kobras
* 9:20 - 9:35 – Wilfried J. J. Meijer, Madrid, ES
+
** Exploring the substrate specificity of the antimicrobial peptide resistance transporter [[BceA]]-[[BceB]] in ''Bacillus subtilis''  
** Studying ''Bacillus subtilis'' plasmid conjugation and its use as a tool for modifying other relevant Gram positive bacteria
+
* 16:45 Luiza P. Morawska
* 9:40 - 9:55 – Trupti Sharma, Bath, UK
+
** Preadaptation of ''Bacillus subtilis'' to mild osmostress contributes to increased antibiotic resistance
** Microbiologically induced calcium carbonate precipitation by extremophilic ''Bacillus'' species – A potential application as microbial agents for the development of self-healing concrete
+
* 17:00 Mary K. Phillips-Jones
* 10:00 - 10:35 - COFFEE BREAK
+
** Characterisation of the VanA-type VanS histidine kinase involved in glycopeptide resistance in Gram-positive bacteria and its ligand interactions
 +
* 17:15 Gabriela Henriques
 +
** Towards the understanding of the regulation of [[SppA]] by [[YteJ]] in Bacillus subtilis.
  
== Session VI: Cell wall and cell biology ==
+
== Free evening in Bath ==
CHAIR: [[Uwe Völker]]
 
* 10:40 - 10:55 – Mike van Nieuwenhze, Bloomington/ Newcastle, USA/ UK
 
** Novel chemical tools for probing the dynamics of peptidoglycan biosynthesis
 
* 11:00 - 11:15 – Henrik Strahl, Newcastle, UK
 
** Polar localization of bacterial chemoreceptors by recruitment to highly curved septal membrane
 
* 11:20 - 11:35 – David Noone, Trinity College Dublin, IE
 
** The [[WalK]] sensor kinase detects several signals during the growth cycle of ''Bacillus subtilis''
 
* 11:40 - 11:55 – Karzan R. Sidiq, Newcastle, UK
 
** A D-alanine transporter in ''Bacillus subtilis''
 
* 12:00 - 12:15 – [[Peter Graumann]], Marburg, DE
 
** [[MreB]] forms curved sheets of filaments that nucleate on membranes ''in vitro''
 
* 12:20 - 12:35 – Jeanine Rismondo, Wernigerode, DE
 
** Discrete and overlapping roles of the five high molecular weight penicillin binding proteins in [[cell division]], growth and virulence of ''Listeria monocytogenes''
 
** 12:40 - 13:40 – LUNCH
 
  
== Session VII: Toxins & antibiotics/ Protection & Resistance ==
+
= Wednesday 13th June =
CHAIR: Sandrine Auger
 
* 13:40 - 13:55 – N. Jahn, Jena, DE
 
** Against the mainstream: The type I toxin [[BsrG]] from ''Bacillus subtilis'' does not disrupt membrane potential although it is recruited to the cell membrane
 
* 14:00 - 14:15 –Yazen Yaseen, Lille, FR
 
** Comparative study of fengycin promoters using green fluorescent protein (GFP) fusion marker
 
* 14:20 - 14:35 –Luminita Ciolacu, KEMIN, BE
 
** Lipopeptides of ''Bacillus subtilis'' PB6 - A comparison of two phenotypes
 
* 14:40 - 14:55—Elrike Frenzel, Groningen, NL
 
** Single cell profiling of cereulide toxin producing ''Bacillus cereus''
 
* 15:00 - 15:15 – [[Anne-Brit Kolsto|Anne-Brit Kolstø]], Oslo, NO
 
** The secret lives of bacterial efflux transporter proteins
 
* 15:20 - 15:35 – [[Susanne Gebhard]], Bath, UK
 
** Need-based activation of antibiotic resistance by a flux-sensing mechanism
 
* 15:40 - 16:00 – COFFEE BREAK
 
  
== Session VIII: Biofilm & Secretion ==
+
== Session 5 Biotechnology ==
CHAIR: [[Kevin Devine]]
+
CHAIR:  Anne Breüner
* 16:00 - 16:15 [[Akos T Kovacs]], University of Jena, DE
+
* 9:00 Andreas Knapp
** Rise to the surface: importance of motility and aerotaxis in pellicle biofilm development
+
** The spacer region in the 5´-UTR strongly affects recombinant protein production in ''Bacillus subtilis''
* 16:20 - 16:35 – Cinzia Calvio, University of Pavia, IT
+
* 9:15 Alexandria Holland
** Four “y” genes in ''B. subtilis'' genome encode γ-PGA hydrolases
+
** Investigating protein secretion in ''Geobacillus thermoglucosidasius''
* 16:40 - 16:55 – Stavroula Balomenou, University of Crete, GR
+
* 9:30 Matthew Styles
** Distinct functions of polysaccharide deacetylases in physiology, virulence and [[biofilm formation]] of ''Bacillus anthracis''
+
** Engineering ''Parageobacillus'' for the Production of Terpenes: Building Better Chassis Organisms for Industrial Biotechnology
* 17:00 - 17:15 – Rita Cruz, DSM Delft, NL
+
* 9:45 Luca Longanesi
** Impact of secretion and wall stress on [[protein secretion]] by ''Bacillus subtilis''
+
** γ-PGA production through Consolidated Bioprocessing in engineered ''B. subtilis'' lab strains
* 17:20 - 17:35 Alexandria Holland, Bath University, UK
+
* 10:00 Matteo Cavaletti
** [[Protein secretion]] in ''Bacillus thermoglucosidasius''
+
** Optimization of γ-PGA biosynthesis supported by synthetic biology and metabolic engineering strategies
* 17:40 - 17:55 – Sara Kesel, University of Munich, DE
+
* 10:15 Ioannis Mougiakos
** Carbohydrate-coating reduces adhesion of biofilm forming ''Bacillus subtilis'' to gold surfaces
+
** Characterizing a thermostable Cas9 for bacterial genome editing and silencing
+
 
* 18:00 Drinks
+
== 10:15 - 10:45 Tea and Coffee ==
 +
 
 +
== Session 6 - [[Sporulation]] and development ==
 +
CHAIR: TBC
 +
* 10:45 [[Imrich Barák]]  
 +
** What we (don’t) know about the asymmetric septum in ''Bacillus subtilis''
 +
* 11:00 Munehiro Asally
 +
** Quality monitoring during [[sporulation]] in ''B. subtilis''
 +
* 11:15 [[Ilka Bischofs]]
 +
** Phenotypic memory links different stages of the ''B. subtilis'' life cycle
 +
* 11:30 [[Akos Kovacs]]  
 +
** Cheating promotes evolution of hyper-cooperators by shifting phenotypic heterogeneity in biofilms
 +
* 11:45 [[Sven Halbedel]]
 +
** Novel ''[[gpsB]]'' suppressor genes contributing to regulatory proteolysis and ''cell division''
 +
* 12:00 Sofia Arnaouteli
 +
** Exploring the role of pulcherrimin in ''Bacillus subtilis'' [[biofilm formation]]
 +
* 12:15 Karin Bjerre
 +
** Investigating of ''Bacillus subtilis'' and ''Bacillus amyloliquefaciens'' spores and vegetative cells in fecal samples from pigs
 +
 
 +
==12:30 – 14:30 Lunch and Poster Session 2 ==
 +
 
 +
==Session 7 – Antibiotics 2 ==
 +
CHAIR:  [[Kevin Devine]]
 +
* 14:30 Auke J. van Heel
 +
** BAGEL4: A user-friendly web server to mine RiPPs and bacteriocins
 +
* 14:45 Amanda Y. van Tilburg
 +
** ''Bacillus subtilis'' as heterologous production host for lantibiotics
 +
* 15:00 Nina Lautenschlaeger
 +
** A novel heterologous whole-cell biosensor in ''Bacillus subtilis'' for the comprehensive detection of b-lactam antibiotics
 +
* 15:15 Marjorie Gibbon
 +
** Towards understanding signalling between the bacitracin resistance transporter [[BceA]]-[[BceB]] and histidine kinase [[BceS]] of ''Bacillus subtilis''
 +
 
 +
== 15:30 – 16:00 Tea and Coffee ==
 +
 
 +
== Session 8 Cereus Group ==
 +
CHAIR:  [[Cinzia Calvio]]
 +
* 16:00 Monika Ehling-Schulz
 +
** ''Bacillus cereus'', a multifaceted pathogen: The challenge of discriminating high and low enteropathogenic strains
 +
* 16:15 Nick Waterfield
 +
** ''Bacillus cereus'' G9241 – to anthrax and back again
 +
* 16:30 Ludivine Rousset
 +
** Oligotrophy induces phenotypic diversification of ''Bacillus cereus'' AH187
 +
* 16:45 Jan Maarten van Dijl
 +
** Can ''Bacillus thuringiensis'' and other microorganisms isolated from chronic wounds ‘pacify’ ''Staphylococcus aureus''?
 +
 
 +
== 17:00 Closing Remarks==
 +
 
 +
== 19:00 – 23:00 Social event at The Terrace, The Roman Baths, generously supported by BACIP – to include the prize giving for best posters and talks from PhD/Postdocs ==
  
* 19:00 Dinner
 
  
 
= END OF MEETING =
 
= END OF MEETING =

Latest revision as of 15:38, 4 June 2018

Tuesday 12th June

  • 8:30 – 8:55 Registration
  • 8:55 Welcome - Chancellors’ Building, room 1.12

Session 1 Regulation

CHAIR: David Leak

  • 09:00 Ciaran Condon
    • Suppression of the essential nature of RNase M16 (YqfG), required for 3' maturation of B. subtilis 16S ribosomal RNA, by deletion of RNase R
  • 09:15 Roland Hartmann
    • Function and regulation of two 6S RNAs in Bacillus subtilis
  • 09:30 Matthias Mack
    • A dual control mechanism synchronizes riboflavin and sulphur metabolism in Bacillus subtilis
  • 09:45 Hermann Rath
    • A SigB-dependent antisense RNA affects osmotic induction of opuB expression in Bacillus subtilis
  • 10:00 Laura Teichmann
    • Suppressor analysis illuminates the structure/function relationship of the glycine betaine synthesis repressor GbsR
  • 10:15 Sylvain Durand
    • sRNA-mediated activation of gene expression by inhibition of 5’-3’exonucleolytic mRNA degradation

10:30 – 11:00 Tea and Coffee - Chancellors’ Building, ground floor foyer

Session 2 Cell division

CHAIR: TBA

  • 11:00 Henrik Strahl
    • Bacillus subtilis does not form microscopically detectable cardiolipin domains
  • 11:15 Jeanine Rismondo
    • Discovery of genes required for lipoteichoic acid glycosylation predicts two distinct mechanism for wall teichoic acid glycosylation
  • 11:30 Edward de Koning
    • Divisome maturation in Bacillus subtilis single cells
  • 11:45 Seamus Holden
  • 12:00 Dirk-Jan Scheffers
  • 12:15 Yongqiang Gao
    • Cell division in the cell wall-less bacterium Acholeplasma laidlawii


12:30 – 14:30 Lunch and Poster Session 1

Session 3 – Interesting Biology

CHAIR: Colin Harwood

  • 14:30 Jörg Stülke
    • DNA topoisomerases in Bacillus subtilis: A tale on mutants and suppressors
  • 14:45 Hannah Gaimster
    • Lethal depletion of essential cell envelope proteins can be rescued by slowing DNA replication in Bacillus subtilis
  • 15:00 Alexandre Deloupy
    • Stochastic gene expression in Bacillus subtilis
  • 15:15 Sabine Schneider
    • Development of a reporter gene system to characterise riboswitch function and to identify riboswitch modulators by high-throughput screening
  • 15:30 Ken-ichi Yoshida
    • Rapid conjugative mobilization of a 100 kb segment of Bacillus subtilis chromosomal DNA is mediated by a helper plasmid with no ability for self-transfer
  • 15:45 Anna A. Toymentseva
    • Mobilization and transfer of plasmids and chromosomal DNA mediated by optimized ICEBs1 conjugative element

16:00 – 16:30 Tea and Coffee

Session 4 – Antibiotics 1

CHAIR: Ulrike Mäder

  • 16:30 Carolin Kobras
    • Exploring the substrate specificity of the antimicrobial peptide resistance transporter BceA-BceB in Bacillus subtilis
  • 16:45 Luiza P. Morawska
    • Preadaptation of Bacillus subtilis to mild osmostress contributes to increased antibiotic resistance
  • 17:00 Mary K. Phillips-Jones
    • Characterisation of the VanA-type VanS histidine kinase involved in glycopeptide resistance in Gram-positive bacteria and its ligand interactions
  • 17:15 Gabriela Henriques
    • Towards the understanding of the regulation of SppA by YteJ in Bacillus subtilis.

Free evening in Bath

Wednesday 13th June

Session 5 Biotechnology

CHAIR: Anne Breüner

  • 9:00 Andreas Knapp
    • The spacer region in the 5´-UTR strongly affects recombinant protein production in Bacillus subtilis
  • 9:15 Alexandria Holland
    • Investigating protein secretion in Geobacillus thermoglucosidasius
  • 9:30 Matthew Styles
    • Engineering Parageobacillus for the Production of Terpenes: Building Better Chassis Organisms for Industrial Biotechnology
  • 9:45 Luca Longanesi
    • γ-PGA production through Consolidated Bioprocessing in engineered B. subtilis lab strains
  • 10:00 Matteo Cavaletti
    • Optimization of γ-PGA biosynthesis supported by synthetic biology and metabolic engineering strategies
  • 10:15 Ioannis Mougiakos
    • Characterizing a thermostable Cas9 for bacterial genome editing and silencing

10:15 - 10:45 Tea and Coffee

Session 6 - Sporulation and development

CHAIR: TBC

  • 10:45 Imrich Barák
    • What we (don’t) know about the asymmetric septum in Bacillus subtilis
  • 11:00 Munehiro Asally
  • 11:15 Ilka Bischofs
    • Phenotypic memory links different stages of the B. subtilis life cycle
  • 11:30 Akos Kovacs
    • Cheating promotes evolution of hyper-cooperators by shifting phenotypic heterogeneity in biofilms
  • 11:45 Sven Halbedel
    • Novel gpsB suppressor genes contributing to regulatory proteolysis and cell division
  • 12:00 Sofia Arnaouteli
  • 12:15 Karin Bjerre
    • Investigating of Bacillus subtilis and Bacillus amyloliquefaciens spores and vegetative cells in fecal samples from pigs

12:30 – 14:30 Lunch and Poster Session 2

Session 7 – Antibiotics 2

CHAIR: Kevin Devine

  • 14:30 Auke J. van Heel
    • BAGEL4: A user-friendly web server to mine RiPPs and bacteriocins
  • 14:45 Amanda Y. van Tilburg
    • Bacillus subtilis as heterologous production host for lantibiotics
  • 15:00 Nina Lautenschlaeger
    • A novel heterologous whole-cell biosensor in Bacillus subtilis for the comprehensive detection of b-lactam antibiotics
  • 15:15 Marjorie Gibbon
    • Towards understanding signalling between the bacitracin resistance transporter BceA-BceB and histidine kinase BceS of Bacillus subtilis

15:30 – 16:00 Tea and Coffee

Session 8 – Cereus Group

CHAIR: Cinzia Calvio

  • 16:00 Monika Ehling-Schulz
    • Bacillus cereus, a multifaceted pathogen: The challenge of discriminating high and low enteropathogenic strains
  • 16:15 Nick Waterfield
    • Bacillus cereus G9241 – to anthrax and back again
  • 16:30 Ludivine Rousset
    • Oligotrophy induces phenotypic diversification of Bacillus cereus AH187
  • 16:45 Jan Maarten van Dijl
    • Can Bacillus thuringiensis and other microorganisms isolated from chronic wounds ‘pacify’ Staphylococcus aureus?

17:00 Closing Remarks

19:00 – 23:00 Social event at The Terrace, The Roman Baths, generously supported by BACIP – to include the prize giving for best posters and talks from PhD/Postdocs

END OF MEETING

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