Difference between revisions of "Program"

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= Sunday June 11, 2017 =
+
= Tuesday 12th June =
  
* 14:00 - 15:00 Registration
+
* 8:30 – 8:55 Registration
* 14:45 - 15:00 – Welcome remarks, [[Jörg Stülke]]
+
* 8:55 Welcome - Chancellors’ Building, room 1.12
  
== Session 1 [[Sporulation]]==
+
== Session 1 Regulation==
CHAIR:  [[Sigal Ben-Yehuda]]
+
CHAIR:  David Leak
* 15:00 - 15:25 [[Richard Losick]]  
+
* 09:00 [[Ciaran Condon]]  
**Stochasticity and cell-fate determination during [[sporulation]] in ''B. subtilis''
+
** Suppression of the essential nature of RNase M16 ([[YqfG]]), required for 3' maturation of ''B. subtilis'' 16S ribosomal RNA, by deletion of [[rnr|RNase R]]
* 15:30 - 15:40 Alper Mutlu
+
* 09:15 [[Roland Hartmann]]
** Phenotypic memory links entry and exit from dormancy by a spore quantity-quality tradeoff in ''Bacillus subtilis''
+
** Function and regulation of two 6S RNAs in Bacillus subtilis
* 15:45 - 15:55 [[Patrick Eichenberger]]
+
* 09:30 [[Matthias Mack]]
** Inferring the ''Bacillus subtilis'' global gene regulation network
+
** A dual control mechanism synchronizes riboflavin and sulphur metabolism in ''Bacillus subtilis''
* 16:00 - 16:10 [[Tony Wilkinson]]
+
* 09:45 Hermann Rath
** Structures of [[SpoIIE]] reveal a regulatory switch shared across the PPC2 phosphatase family and extending to the proteasomal proteases
+
** A [[SigB]]-dependent antisense RNA affects osmotic induction of ''[[opuBA|opuB]]'' expression in ''Bacillus subtilis''
* 16:15 - 16:25 David Roberts
+
* 10:00 Laura Teichmann
** Polar segregation of the chromosome origins during [[sporulation]] in ''Bacillus subtilis''
+
** Suppressor analysis illuminates the structure/function relationship of the glycine betaine synthesis repressor [[GbsR]]
* 16:30 - 16:40 Anna Grela
+
* 10:15 Sylvain Durand
** Functional analysis of [[GerAA]] subunit of ''Bacillus subtilis'' GerA [[germination]] receptor
+
** sRNA-mediated activation of gene expression by inhibition of 5’-3’exonucleolytic mRNA degradation
* 16:45 - 16:55 Eammon Riley
 
** Defining the metabolic landscape of the ''Bacillus subtilis'' sporangium
 
  
== 17:00 Welcome reception==
+
== 10:30 – 11:00 Tea and Coffee - Chancellors’ Building, ground floor foyer==
  
= Monday June 12, 2017 =
+
== Session 2 [[Cell division]]==
 +
CHAIR:  TBA
 +
* 11:00 [[Henrik Strahl]]
 +
** ''Bacillus subtilis'' does not form microscopically detectable cardiolipin domains
 +
* 11:15 Jeanine Rismondo
 +
** Discovery of genes required for lipoteichoic acid glycosylation predicts two distinct mechanism for wall teichoic acid glycosylation
 +
* 11:30 Edward de Koning
 +
** [[Divisome]] maturation in ''Bacillus subtilis'' single cells
 +
* 11:45 Seamus Holden
 +
** Treadmilling by [[FtsZ]] filaments drives ''Bacillus subtilis'' [[cell wall synthesis|peptidoglycan synthesis]] and bacterial [[cell division]]
 +
* 12:00 [[Dirk-Jan Scheffers]]
 +
** [[PbpB|PBP2B]] [[PASTA domains]] interact with [[DivIB]] to stabilize [[cell division]]
 +
* 12:15 Yongqiang Gao
 +
** [[Cell division]] in the cell wall-less bacterium ''Acholeplasma laidlawii''
  
== Session 2 Cell biology 1 ==
 
CHAIR: [[Dirk-Jan Scheffers]]
 
* 08:30 - 08:55 [[Jan Willem Veening]]
 
** Identification of a unique cell cycle regulator in ''Streptococcus pneumoniae'' by en masse GFP localization and CRISPRi phenotyping
 
* 09:00 - 09:10 [[Kumaran Ramamurthi]]
 
** An essential ''Staphylococcus aureus'' [[cell division]] protein regulates both [[FtsZ]] assembly and disassembly
 
* 09:15 - 09:25 Elhanan Tzipilevich
 
** Acquisition of phage sensitivity by bacteria through exchange of phage receptors
 
* 09:30 - 09:40 Lauren Cowley
 
** Evidence for different rates in the mechanisms of recombination in pneumoccal biofilms
 
* 09:45 - 09:55 Nada Labajova
 
** Clostridial Min system – possible mechanism of functioning during [[cell division]] and [[sporulation]]
 
* 10:00 - 10:10 Kenneth Seistrup
 
** Lysis induced by membrane depolarisation is caused by [[MreB]]-linked mis-regulation of key autolysins in ''Bacillus subtilis''
 
  
* 10:15 - 10:45 Coffee break
+
== 12:30 – 14:30 Lunch and Poster Session 1==
== Session 3 Biotechnology ==
 
CHAIR: [[Oscar Kuipers]]
 
* 10:45 - 11:10 [[Daniel Lopez]]
 
** Lipid rafts: From structural and functional characterization to biotechnological application
 
* 11:15 - 11:25 Marcus Price
 
** CRISPR-Cas9 mediated engineering of industrially relevant ''Bacillus subtilis'' strains
 
* 11:30 - 11:40 Rocio Aguilar Suarez
 
** Less is more: towards development of a genome-reduced ''Bacillus'' as cell factory for vaccine production
 
* 11:45 - 11:55 Marta Irla
 
** Methanol-based production γ-aminobutyric acid in ''B. methanolicus'' MGA3
 
* 12:00 - 12:10 Rita Cruz
 
** A comparative study of native and heterologous enzyme production in ''Bacillus subtilis''
 
  
* 12:30 - 14:00 Lunch
+
== Session 3 – Interesting Biology ==
 
+
CHAIR: [[Colin Harwood]]
== Session 4 New technologies, Systems & Synthetic Biology ==
+
* 14:30 [[Jörg Stülke]]  
CHAIR: [[Fabian Commichau]]
+
** DNA topoisomerases in ''Bacillus subtilis'': A tale on mutants and suppressors
* 14:00 - 14:25 Carol Gross
+
* 14:45 Hannah Gaimster
** High throughput phenotyping in ''Bacillus subtilis''
+
** Lethal depletion of essential cell envelope proteins can be rescued by slowing [[DNA replication]] in ''Bacillus subtilis''
* 14:30 - 14:40 Christopher Zschiedrich
+
* 15:00 Alexandre Deloupy
** Large scale identification of evolutionary mechanism that facilitate protein-protein [[interactions]]
+
** Stochastic gene expression in Bacillus subtilis
* 14:45 - 14:55 [[Leendert Hamoen]]  
+
* 15:15 Sabine Schneider
** Construction of a minimal [[divisome]] reveals robustness of [[cell division]]
+
** Development of a reporter gene system to characterise [[riboswitch]] function and to identify [[riboswitch]] modulators by high-throughput screening
* 15:00 - 15:10 Etienne Dervyn
+
* 15:30 [[Ken-ichi Yoshida]]  
** Tailoring ''Bacillus subtilis''-derived chassis for biotechnology applications
+
** Rapid conjugative mobilization of a 100 kb segment of ''Bacillus subtilis'' chromosomal DNA is mediated by a helper plasmid with no ability for self-transfer
* 15:15 - 15:25 Jan Martinussen
+
* 15:45 Anna A. Toymentseva
** Abrupt glucose depletion in ''Lactococcus lactis'' is resulting in an immediate translational stop due to an extreme depletion of the GTP pool
+
** Mobilization and transfer of plasmids and chromosomal DNA mediated by optimized ICEBs1 conjugative element
* 15:30 - 15:40 Eugen Peifer
 
** Adaptive laboratory evolution of ''Corynebacterium glutamicum'' towards higher growth rates on glucose minimal medium
 
 
* 15:45 - 16:15 Coffee break
 
== Session 5 Cell Biology 2==
 
CHAIR: [[Stephane Aymerich]]
 
* 16:15 - 16:25 [[Sven Halbedel]]
 
** Peptidoglycan N-deacetylation is jointly controlled by [[PgdA]], PBP A1 and [[GpsB]] in ''Listeria monocytogenes''
 
* 16:30 - 16:40 [[Rick Lewis]]
 
** Exploring the relationship between [[penicillin binding proteins]] and the cell cycle regulator, [[GpsB]]
 
* 16:45 - 16:55 [[Peter Graumann]]
 
** ''B. subtilis'' chromosomes are segregated in in a directed diffusion-like manner, likely based on entropic forces, and are condensed by several SMC condensation centres per cell half, as revealed through single molecule tracking
 
* 17:00 - 17:10 Koichi Yano
 
** ''cis''-acting rDNA act as a loading site for [[Smc]]-[[ScpA]]-[[ScpB]] during nucleoid separation in ''Bacillus subtilis''
 
* 17:15 - 17:25 [[Marc Bramkamp]]
 
** A dynamin-like protein involved in bacterial cell membrane surveillance under environmental stress
 
 
 
== Poster Session 1 ==
 
* 17:30 - 19:30
 
 
 
= Tuesday June 13, 2017 =
 
== Session 6 Signal transduction ==
 
CHAIR: [[Ivan Mijakovic]]
 
* 08:30 - 08:40 Jörgen Johansson
 
** Structural and genetic basis for activation and repression of the virulence activator PrfA in ''Listeria monocytogenes''
 
* 08:45 - 08:55 [[Nathalie Declerck]]
 
** Monitoring transcriptional adaptation in live ''Bacillus subtilis'' cells using two-photon fluorescence fluctuation microscopy
 
* 09:00 - 09:10 Jan Gundlach
 
** Cyclic di-AMP controls potassium homeostasis in ''Bacillus subtilis''
 
* 09:15 - 09:25 [[Sylvie Nessler]]
 
** Structural insights into streptococcal competence regulation by the cell-to-cell communication system ComRS
 
* 09:30 - 09:40 Johann Mignolet
 
** Ubiquitous rewiring of transcriptional control in streptococci: lesson from competence and predation coupling in ''Streptococcus salivarius''
 
* 09:45 - 09:55 [[Craig Ellermeier]]
 
** [[RsiV]] is a bacterial receptor for lysozyme
 
* 10:00 - 10:10 Christopher Rao
 
** DNA sensing in ''Bacillus subtilis''
 
 
 
*10:15 - 10:45 Coffee break
 
== Session 7 RNA Biology ==
 
CHAIR: [[Christiane Wolz]]
 
* 10:45 - 11:10 Pascale Romby
 
** Several regulatory RNAs in ''Staphylococcus aureus ''link stress responses, metabolism and virulence factor synthesis
 
* 11:15 - 11:25 Ruben Atilho
 
** A widespread [[riboswitch]] class regulates guanidine metabolism in bacteria
 
* 11:30 - 11:40 [[Emma Denham]]
 
** Towards the ''in vivo'' RNA interactome of the Gram positive model organism ''Bacillus subtilis''
 
* 11:45 - 11:55 [[Libor Krasny]]
 
** The torpedo effect in [[Bacillus subtilis]]: RNase J1 resolves stalled [[transcription]] complexes
 
* 12:00 - 12:10 [[Ciaran Condon]]
 
** Rae1/[[YacP]], a new endoribonuclease involved in [[ribosome]]-dependent mRNA decay in ''B. subtilis''
 
 
*12:30 - 14:00 Lunch
 
== Session 8 Metabolism ==
 
CHAIR: [[Lars Hederstedt]]
 
* 14:00 - 14:10 Miriam Dormeyer
 
** A devil in disguise: a metabolic enzyme converts a transcriptional activator into a repressor
 
* 14:15 - 14:25 Lianet Noda-Garcia
 
** Mapping of chance and necessity in protein sequence evolution in complex bacterial environments
 
* 14:30 - 14:40 [[Georg Fritz]]
 
** Making and breaking the wall – a systems approach to cell wall homeostasis in ''Bacillus subtilis''
 
* 14:45 - 14:55 [[Christoph Mayer]]  
 
** Peptidoglycan recycling in Gram-positive bacteria is crucial for survival
 
* 15:00 - 15:10 Amy Bottomley
 
** We are what we eat: Identifying a regulatory crosstalk between central carbon metabolism and [[cell division]] in bacteria
 
* 15:15 - 15:25 Ines Grilo
 
** Glucosaminidase-DNA interaction affects the peptidoglycan hydrolytic activity of glucosaminidase
 
* 15:30 - 15:40 Daisuke Seo
 
** Purification and characterization of ferredoxin-NADPH oxidoreductase paralogue [[YcgT]] in gram-positive bacterium ''Bacillus subtilis''
 
 
* 15:45 - 16:15 Coffee break
 
 
 
== Session 9 Lifestyles I - Stress ==
 
CHAIR: [[Susanne Gebhard]]
 
* 16:15 - 16:40 [[Jade Wang]]  
 
** Regulation of stress response and homeostasis by (p)ppGpp in ''Bacillus subtilis''
 
* 16:45 - 16:55 [[Gerd Bange]]
 
** Structural and functional insights into the (p)ppGpp response of ''B. subtilis''
 
* 17:00 - 17:10 Jose A. Lemos
 
** The association of metal homeostasis and (p)ppGpp regulation in the pathophysiology of ''Enterococcus faecalis''
 
* 17:15 - 17:25 Alexander Reder
 
** New insights into the general stress response of ''Bacillus subtilis'' - the [[SigB]] modulon
 
 
 
== Poster Session 2 ==
 
* 17:30 - 19:30
 
 
 
= Wednesday June 14, 2017 =
 
== Session 10 Lifestyles II - Biofilm==
 
CHAIR: [[Ilka Bischofs]]
 
* 08:30 - 08:40 Polonca Stefanic
 
** Kin discrimination foretells ''B. subtilis'' lifestyles
 
* 08:45 - 08:55 Nozomu Obana
 
** Heterogeneity and biofilm morphology in ''Clostridium perfringens''
 
* 09:00 - 09:10 Sofia Arnaouteli
 
** Bifunctionality of a biofilm matrix protein controlled by redox state
 
* 09:15 - 09:25 Anna Dragos
 
** Collapse of genetic division of labor and evolution of autonomy in pellicle biofilms
 
* 09:30 - 09:40 Tamara Hoffmann
 
** Small but essential: the activator protein [[RemA]] links [[biofilm formation]] and osmostress responses in ''Bacillus subtilis''
 
* 09:45 - 09:55 [[Harald Putzer]]
 
** Swarmer cells lead, multiply and generate a trail of quiescent descendants
 
* 10:00 - 10:10 Pascale Beauregard
 
** Biofilm and bacillibactin are essential to iron homeostasis in ''Bacillus subtilis''
 
 
 
* 10:15 - 10:45 Coffee break
 
 
 
== Session 11 DNA replication and recombination/ Interactions with other organisms==
 
CHAIR: [[xxx]]
 
* 10:45 - 10:55 Mary Anderson
 
** Suppression of [[DNA replication]] overinitiation through lowered levels of the replicative helicase, [[DnaC]]
 
* 11:00 - 11:10 [[Juan Alonso]]
 
** ''Bacillus subtilis'' [[MutS]] modulates non-polar recombination between divergent DNA sequences
 
* 11:15 - 11:25 Paul Straight
 
** Antibiotic stimulation of a ''Bacillus subtilis'' motile response
 
* 11:30 - 11:40 Audrey Labarde
 
** Remodelling of the ''Bacillus subtilis'' cytoplasm spatial organization for efficient bacteriophage SPP1 multiplication
 
* 11:45 - 11:55 [[Elisabeth Grohmann]]
 
** Molecular insights in conjugative resistance transfer among Gram-positive pathogens
 
* 12:00 - 12:10 Javier Pizarro-Cerda
 
** A bacteriocin from epidemic ''Listeria'' strains alters the host intestinal microbiota to favor infection
 
 
 
* 12:30 - 14:00 Lunch
 
 
 
== Session 12 The ''Bacillus cereus'' group==
 
CHAIR: [[Theresa Koehler]]
 
* 14:00 - 14:25 Didier Lereclus
 
** High throughput phenotyping in Bacillus subtilis
 
* 14:30 - 14:40 Naomi Bier The Influence of the PEP-PTS on Virulence Gene Expression in Bacillus anthracis
 
* 14:45 - 14:55 Sandrine Poncet Hanks-kinases dependent phosphorylation of Bacillus cereus global gene regulator CodY deeply impacts physiology and virulence
 
* 15:00 - 15:10 Monika Ehling-Schulz Food Bacteria Interplay: Concerted action of extrinsic and extrinsic factors gearing toxin synthesis in emetic Bacillus cereus
 
* 15:15 - 15:25 Joaquin Caro-Astorga Analysis of the molecular machinery implicated in multicellularity in Bacillus cereus
 
* 15:30 - 15:40 David Sychantha Structural and mechanistic basis for the O-acetylation of secondary cell wall polysaccharide required for the proper assembly of cell walls in the Bacillus cereus group of human pathogens
 
 
 
* 15:45 - 16:15 Coffee break
 
Session Pathogenicity/ fighting infection
 
16:15 - 16:25 Tarek Msadek Bacteriophage mobility and pathogenesis in Staphylococcus aureus
 
16:30 - 16:40 Van Loi Vu Real-time imaging of the bacillithiol redox potential in the human pathogen Staphylococcus aureus using a genetically encoded bacilliredoxin-fused redox biosensor
 
16:45 - 16:55 Laty Cahoon A structural comparison of Listeria monocytogenes secretion chaperones PrsA1 and PrsA2 reveals molecular features required for virulence
 
17:00 - 17:10 Leanne Hays Biofilm formation by the staphylococcal protein SdrC: molecular mechanism and the identification of novel inhibitors
 
17:15 - 17:25 Emanuel Hanski Integration of host and bacterial signals controls group A streptococcal bacteriocins production to establish dominance in the fascial niche
 
Conference dinner
 
19:00 - 23:00
 
 
 
= Thursday June 15, 2017 =
 
 
 
Session Lifestyles III
 
08:30 - 08:40 Sabine Brantl Type I toxin-antitoxin systems from Bacillus subtilis
 
08:45 - 08:55 Michael Prunty Distinct PhoPR-mediated responses to phosphate limitation in Bacillus subtilis subspecies subtilis and spizizenii stem from differences in their anionic polymer composition and metabolism
 
09:00 - 09:10 Kursad Turgay Curbing protein synthesis is important for the concerted heat shock response of Bacillus subtilis
 
09:15 - 09:25 Thorsten Mascher Three's Company: Cannibalism Toxins and the Corresponding Envelope Stress Responses in Bacillus subtilis
 
09:30 - 09:40 Daniel Rojas Induction of the Spx regulon under cell wall stress requires both an ECF sigma factor and an anti-adaptor protein
 
09:45 - 09:55 Brandon Anjuwon-Foster The DNA recombinase RecV mediates phase variation of Clostridium difficile flagellum and toxin production
 
10:00 - 10:10 Ard Jan Grimbergen Bet-hedging strategies in Bacillus subtilis
 
10:15 - 10:45 Coffee break
 
Session Organizers' favorites
 
10:45 - 11:10 Emanuelle Charpentier CRISPR-Cas9: a bacterial immune system repurposed as a transformative genome engineering technology
 
 
11:15 - 11:25 Ken-Ichi Yoshida Geobacillus kaustophilus Crh is independent of glucose catabolite repression but represses inositol catabolic genes
 
11:30 - 11:40 Patricia Dos Santos Mutual specificity of cysteine desulfurases and sulfur acceptors in Bacillus subtilis
 
* 11:45 - 11:55 Richard Daniel D-ala metabolism in Bacillus subtilis
 
* 12:00 - 12:10 Anne-Brit Kolsto The putative drug efflux systems of the Bacillus cereus group
 
12:30 - 14:00 Lunch
 
  
 +
==16:00 – 16:30 Tea and Coffee ==
 +
 +
==Session 4 – Antibiotics 1 ==
 +
CHAIR:  [[Ulrike Mäder]]
 +
* 16:30 Carolin Kobras
 +
** Exploring the substrate specificity of the antimicrobial peptide resistance transporter [[BceA]]-[[BceB]] in ''Bacillus subtilis''
 +
* 16:45 Luiza P. Morawska
 +
** Preadaptation of ''Bacillus subtilis'' to mild osmostress contributes to increased antibiotic resistance
 +
* 17:00 Mary K. Phillips-Jones
 +
** Characterisation of the VanA-type VanS histidine kinase involved in glycopeptide resistance in Gram-positive bacteria and its ligand interactions
 +
* 17:15 Gabriela Henriques
 +
** Towards the understanding of the regulation of [[SppA]] by [[YteJ]] in Bacillus subtilis.
  
= Monday June 22, 2015 =
+
== Free evening in Bath ==
  
* 8:15 - 8:30 – Welcome remarks, [[Jim Hoch]], [[Marta Perego]]
+
= Wednesday 13th June =
* 8:30 - 9:15 - Keynote lecture: Andrew Camilli, Boston, USA
 
** The ''Streptococcus pneumoniae'' cell wall controls pneumolysin release and contributes to virulence.
 
== Session I Signal transduction I==
 
CHAIR:  [[Marta Perego]]
 
* 9:15 - 9:30 – [[Kevin Devine]], Dublin, Ireland
 
** The activities of the [[WalR]]-[[WalK]] and [[PhoP]]-[[PhoR]] [[two-component systems|two-component signal transduction systems]] are determined by signals that emanate from cell wall metabolism in ''Bacillus subtilis''
 
* 9:30 - 9:45 – [[Hendrik Szurmant]], La Jolla. USA
 
** The [[YycF]]-[[YycG]] [[two-component systems|two-component system]] as a regulatory feedback loop for the expression of autolysin activity and the target of antimicrobial activities by human chemokines.
 
* 9:45 - 10:00 – [[Tarek Msadek]], Paris, France
 
** Peptide antibiotic resistance and intramembrane kinase signaling in ''Staphylococcus aureus''.
 
  
* 10:00 10:30 – COFFEE BREAK
+
== Session 5 Biotechnology ==
 +
CHAIR:  Anne Breüner
 +
* 9:00 Andreas Knapp
 +
** The spacer region in the 5´-UTR strongly affects recombinant protein production in ''Bacillus subtilis''
 +
* 9:15 Alexandria Holland
 +
** Investigating protein secretion in ''Geobacillus thermoglucosidasius''
 +
* 9:30 Matthew Styles
 +
** Engineering ''Parageobacillus'' for the Production of Terpenes: Building Better Chassis Organisms for Industrial Biotechnology
 +
* 9:45 Luca Longanesi
 +
** γ-PGA production through Consolidated Bioprocessing in engineered ''B. subtilis'' lab strains
 +
* 10:00 Matteo Cavaletti
 +
** Optimization of γ-PGA biosynthesis supported by synthetic biology and metabolic engineering strategies
 +
* 10:15 Ioannis Mougiakos
 +
** Characterizing a thermostable Cas9 for bacterial genome editing and silencing
  
== Session II Signal transduction II ==
+
== 10:15 - 10:45 Tea and Coffee ==
CHAIR: [[Kevin Devine]]
 
* 10:30 - 10:45 – Mary K. Phillips-Jones, Preston, UK
 
** Characterization of ligand binding by VanS, the membrane sensor kinase of the [[two-component systems|two-component system]] regulating A-type vancomycin resistance in the enterococci.
 
* 10:45 - 11:00 – Emanuel Hanski, Jerusalem, Israel
 
** Regulation of group A ''Streptococcus'' virulence by sensing of asparagines.
 
* 11:00 - 11:15 – Nicola Horstmann, Houston, USA
 
** Regulation of dual-site phosphorylation of response regulator CovR and its impact on group A streptococcus global gene expression and virulence.
 
* 11:15 - 11:30 – Andrew Ulijasz, London, UK
 
** A novel family of [[two-component systems|two-component like]] redox sensors in the Streptococci.
 
* 11:30 - 11:45 – [[Marta Perego]], La Jolla, USA
 
** Media-dependent regulation of ''Bacillus anthracis'' toxin gene expression by the [[ResD]]-[[ResE]]-controlled respiration pathway.
 
* 11:45 - 12:00 – Maria Cecilia Manilla, Rosario, Argentina
 
** Proline residues of [[DesK]] as transmitting elements of cold stimulus.
 
* 12:00 - 12:15 – [[Ken-ichi Yoshida]], Kobe, Japan
 
** Hyperphosphorylation of [[DegU]] interferes with [[CcpA]]-dependent catabolite repression of ''[[rocG]]'' in ''Bacillus subtilis''.
 
  
* 12:30 – 14:00 LUNCH
+
== Session 6 - [[Sporulation]] and development ==
== Parallel sessions ==
+
CHAIR:  TBC
=== Session IIIA Industrial Research  (Sala A)===
+
* 10:45 [[Imrich Barák]]  
CHAIR:  Ghislain Schyns
+
** What we (don’t) know about the asymmetric septum in ''Bacillus subtilis''
* 14:00 - 14:45 – Keynote lecture: Sven Panke, Zürich, Switzerland
+
* 11:00 Munehiro Asally
** tba
+
** Quality monitoring during [[sporulation]] in ''B. subtilis''  
* 14:45 - 15:00 – Abderahmane Derouiche, Gothenburg, Sweden
+
* 11:15 [[Ilka Bischofs]]
** ''Bacillus subtilis'' [[SalA]] is a phosphorylation-dependent transcription factor that regulates the production of the exoprotease [[AprE]].
+
** Phenotypic memory links different stages of the ''B. subtilis'' life cycle
* 15:00 - 15:15 –Jolanda Neef, Groningen, Netherlands
+
* 11:30 [[Akos Kovacs]]
** A novel expression platform for the production of cell wall-bound and secreted staphylococcal antigens.
+
** Cheating promotes evolution of hyper-cooperators by shifting phenotypic heterogeneity in biofilms
* 15:15 - 15:30 – Ferro Iolanda, Potsdam, Germany
+
* 11:45 [[Sven Halbedel]]  
** tRNA abundance and aminoacylation in ''Bacillus licheniformis''.
+
** Novel ''[[gpsB]]'' suppressor genes contributing to regulatory proteolysis and ''cell division''
* 15:30 - 15:45 –Birgit Voigt, Greifswald, Germany
+
* 12:00 Sofia Arnaouteli
** The response of ''Bacillus pumilus'' to hydrogen peroxide-provoked oxidative stress.
+
** Exploring the role of pulcherrimin in ''Bacillus subtilis'' [[biofilm formation]]
 
+
* 12:15 Karin Bjerre
=== Session IIIB Host-Pathogen Interaction (Sala B)===
+
** Investigating of ''Bacillus subtilis'' and ''Bacillus amyloliquefaciens'' spores and vegetative cells in fecal samples from pigs
CHAIR:  Claire Poyart
 
* 14:00 - 14:15 – Nancy Freitag, Chicago, USA
 
** Establishing a new niche for bacterial replication: the surface invasin InlB confers cardiotropism to subpopulations of ''Listeria monocytogenes''.
 
* 14:15 - 14:30 – B. S. Hisey, Bozeman, Montana, USA
 
** Role of SaeR/S in secondary ''Staphylococcus aureus'' pneumonia.
 
* 14:30 - 14:45 – Anthony Richardson, Chapel Hill, NC, USA
 
** PPAR-γ is central to the effective host response to ''Staphylococcus aureus'' skin and soft tissue infections.
 
* 14:45 - 15:00 – A.P.A. Hendrickx, Utrecht, Netherlands
 
** Antibiotics-driven dysbiosis mediate alternative segregation of ''Enterococcus faecium'' from the intestinal epithelium.
 
* 15:00 - 15:15 –Mariana Martins, Paris, France
 
** ''Streptococcus gallolyticus'' Pil3 pilus is required for adhesion to colonic mucus and for colonization of mouse distal colon.
 
* 15:15 - 15:30 – Salai Madhumathi Parkunan, Oklahoma City, USA
 
** ''Bacillus'' intraocular infection: Divergent roles of IL6 and CXCL1.
 
* 15:30 - 15:45 – Michelle C. Callegan, Oklahoma City, USA
 
** The role of pili in ''Bacillus cereus'' intraocular infection.
 
 
 
* 15:45 - 16:15 - COFFEE BREAK
 
 
 
== Session IV: Vaccines ==
 
CHAIR: Guido Grandi
 
* 16:15 - 16:30 – Fabio Bagnoi, Siena, Italy
 
** Vaccine composition formulated with a novel TLR7-dependent adjuvant induces high and broad protection against ''Staphylococcus aureus''.
 
* 16:30 - 16:45 – Olaf Schneewind, Chicago, USA
 
** Protein A suppresses immune responses during ''Staphylococcus aureus'' bloodstream infection in guinea pigs.
 
* 16:45 - 17:00 – Johannes Hübner, Munich, Germany
 
** Towards a vaccine against enterococci: Reverse vaccinology and beyond.
 
* 17:00 - 17:15– Edmondo Campisi, Siena, Italy
 
** Structural and genetic characterization of the Type IX Group B ''Streptococcus'' capsular polysaccharide and its relationship with types V and VII
 
* 17:15 - 17:30 – Joseph J. Zeppa, London, Ontario, Canada
 
** Vaccine approaches targeting colonization by ''Streptococcus pyogenes''.
 
 
 
== 17.30 - 19.30 Poster Session I==
 
 
 
= Tuesday June 23, 2015 =
 
 
 
== Parallel sessions ==
 
=== Session VA [[Sporulation]] (Sala A)===
 
CHAIR:  [[Colin Harwood]]
 
* 8:30 - 8:45 [[Charles Moran]], Atlanta, USA
 
** Dual-specificity anti-[[sigma factor]] reinforces control of cell-type specific gene expression in ''Bacillus subtilis''.
 
* 8:45 - 9:00 – Adriano Henriques, Oeiras, Portugal
 
** Single cell analysis of the pathogenicity locus unravels the relationship between toxin production and spore formation in ''Costridium difficile''.
 
* 9:00 - 9:15 – Adrianne Edwards, Atlanta, USA
 
** A putative transcription factor containing conserved tetratricopeptide repeat domains controls [[sporulation]], motility and toxin production in ''Clostridium difficile''.
 
* 9:15 - 9:30 – James R. Walker, Austin, USA
 
** Genomics of ''Clostridium taeniosporum'', an organism which forms spores with a bundle of ribbon-like appendages.
 
* 9:30 - 9:45 – [[Leendert Hamoen]], Amsterdam, Netherlands
 
** Deep starvation reveals a surprisingly active ''Bacillus subtilis'' growth state.
 
* 9:45 - 10:00 – Didier Lereclus, Joyu-en-Josas, France
 
** Division of labour and terminal differentiation in ''Bacillus thuringiensis''.
 
* 10:00 - 10:15 – Nils Widderich, Marburg, Germany
 
** Dysfunctional [[SigH]] prevents entry of ''B. subtilis'' into [[sporulation]] at high salinity.
 
* 10:15 - 10:30 – Tsutomu Sato, Tokyo, Japan
 
** Developmentally-regulated prophage excisions reconstitute genes required for [[sporulation]] in spore-forming bacteria.
 
  
=== Session VB Antimicrobials/ Drug research (Sala B)===
+
==12:30 – 14:30 Lunch and Poster Session 2 ==
CHAIR:  Olaf Schneewind
 
* 8:30 - 8:45 – Eric A. Johnson, Madison, USA
 
** Characterization of a novel chimeric Botulinum neurotoxin.
 
* 8:45 - 9:00 – [[Oscar Kuipers]], Groningen, Netherlands
 
** Cycling with lantibiotics, and potentiating them against Gram-negative pathogens.
 
* 9:00 - 9:15 – A. L. Flores-Mireles, St. Louis, USA
 
** A novel therapy that prevents and resolves ''E. faecalis'' catheter-associated urinary tract infections.
 
* 9:15 - 9:30 – Alexandra Gruss, Jouy-en-Josas, France
 
** Strategies used by ''Staphylococcus aureus'' to bypass FASII-targeted antimicrobials.
 
* 9:30 - 9:45 – Hanne Ingmer, Frederiksberg, Denmark
 
** The ''Staphylococcus aureus agr'' [[quorum sensing]] system as a target for anti-virulence therapy.
 
* 9:45 - 10:00 – Grace Spatafora, Middlebury, USA
 
** Characterizing the SloR-DNA binding interface in ''S. mutans'': A target for rational drug design?
 
* 10:00 - 10:15 – C. Gallay, Groningen, Netherlands
 
** Lack of pAp phosphatase and inhibition of lipid precursors synthesis lead to mislocalization of key [[cell division]] proteins in ''Streptococcus pneumoniae''.
 
* 10:15 - 10:30 – Yoann Le Breton, College Park, MD, USA
 
** Using ''Tn''-seq analyses of divergent group A streptococcal isolates for whole-genome studies of fitness and pathogenesis.
 
  
* 10:30 - 11:00 - COFFEE BREAK
+
==Session 7 – Antibiotics 2 ==
 +
CHAIR:  [[Kevin Devine]]
 +
* 14:30 Auke J. van Heel
 +
** BAGEL4: A user-friendly web server to mine RiPPs and bacteriocins
 +
* 14:45 Amanda Y. van Tilburg
 +
** ''Bacillus subtilis'' as heterologous production host for lantibiotics
 +
* 15:00 Nina Lautenschlaeger
 +
** A novel heterologous whole-cell biosensor in ''Bacillus subtilis'' for the comprehensive detection of b-lactam antibiotics
 +
* 15:15 Marjorie Gibbon
 +
** Towards understanding signalling between the bacitracin resistance transporter [[BceA]]-[[BceB]] and histidine kinase [[BceS]] of ''Bacillus subtilis''
  
== Session VI: Stress ==
+
== 15:30 – 16:00 Tea and Coffee ==
CHAIR: Indranil Biswas
 
* 11:00 - 11:15 – Zehava Eichenbaum, Atlanta, USA
 
** Preventing the red menace: the contributions of streptococcal ''pefRCD'' operon in heme stress survival.
 
* 11:15 - 11:30 – Barbara Spellerberg, Ulm, Germany
 
** A Streptococcal NRAMP homolog is crucial for the survival of ''Streptococcus agalactiae'' under low pH conditions.
 
* 11:30 - 11:45 – Agnes Fouet, Paris, France
 
** [[PerR]] is necessary for full virulence of ''Streptococcus agalactiae''.
 
* 11:45 - 12:00 – Melissa E. Reardon-Robinson, Houston, TX, USA
 
** Oxidative folding of virulence determinants in Gram-positive bacteria.
 
  
* 12:30 – 14:00 LUNCH
+
== Session 8 – Cereus Group ==
 +
CHAIR:  [[Cinzia Calvio]]
 +
* 16:00 Monika Ehling-Schulz
 +
** ''Bacillus cereus'', a multifaceted pathogen: The challenge of discriminating high and low enteropathogenic strains
 +
* 16:15 Nick Waterfield
 +
** ''Bacillus cereus'' G9241 – to anthrax and back again
 +
* 16:30 Ludivine Rousset
 +
** Oligotrophy induces phenotypic diversification of ''Bacillus cereus'' AH187
 +
* 16:45 Jan Maarten van Dijl
 +
** Can ''Bacillus thuringiensis'' and other microorganisms isolated from chronic wounds ‘pacify’ ''Staphylococcus aureus''?
  
== Session VII: Toxins & antibiotics/ Protection & Resistance ==
+
== 17:00 Closing Remarks==
CHAIR: Sandrine Auger
 
* 13:40 - 13:55 – N. Jahn, Jena, DE
 
** Against the mainstream: The type I toxin [[BsrG]] from ''Bacillus subtilis'' does not disrupt membrane potential although it is recruited to the cell membrane
 
* 14:00 - 14:15 –Yazen Yaseen, Lille, FR
 
** Comparative study of fengycin promoters using green fluorescent protein (GFP) fusion marker
 
* 14:20 - 14:35 –Luminita Ciolacu, KEMIN, BE
 
** Lipopeptides of ''Bacillus subtilis'' PB6 - A comparison of two phenotypes
 
* 14:40 - 14:55—Elrike Frenzel, Groningen, NL
 
** Single cell profiling of cereulide toxin producing ''Bacillus cereus''
 
* 15:00 - 15:15 – [[Anne-Brit Kolsto|Anne-Brit Kolstø]], Oslo, NO
 
** The secret lives of bacterial efflux transporter proteins
 
* 15:20 - 15:35 – [[Susanne Gebhard]], Bath, UK
 
** Need-based activation of antibiotic resistance by a flux-sensing mechanism
 
* 15:40 - 16:00 – COFFEE BREAK
 
  
== Session VIII: Biofilm & Secretion ==
+
== 19:00 – 23:00 Social event at The Terrace, The Roman Baths, generously supported by BACIP – to include the prize giving for best posters and talks from PhD/Postdocs ==
CHAIR: [[Kevin Devine]]
 
* 16:00 - 16:15 [[Akos T Kovacs]], University of Jena, DE
 
** Rise to the surface: importance of motility and aerotaxis in pellicle biofilm development
 
* 16:20 - 16:35 – Cinzia Calvio, University of Pavia, IT
 
** Four “y” genes in ''B. subtilis'' genome encode γ-PGA hydrolases
 
* 16:40 - 16:55 – Stavroula Balomenou, University of Crete, GR
 
** Distinct functions of polysaccharide deacetylases in physiology, virulence and [[biofilm formation]] of ''Bacillus anthracis''
 
* 17:00 - 17:15 – Rita Cruz, DSM Delft, NL
 
** Impact of secretion and wall stress on [[protein secretion]] by ''Bacillus subtilis''
 
* 17:20 - 17:35 – Alexandria Holland, Bath University, UK
 
** [[Protein secretion]] in ''Bacillus thermoglucosidasius''
 
* 17:40 - 17:55 Sara Kesel, University of Munich, DE
 
** Carbohydrate-coating reduces adhesion of biofilm forming ''Bacillus subtilis'' to gold surfaces
 
 
* 18:00 Drinks
 
  
* 19:00 Dinner
 
  
 
= END OF MEETING =
 
= END OF MEETING =

Latest revision as of 15:38, 4 June 2018

Tuesday 12th June

  • 8:30 – 8:55 Registration
  • 8:55 Welcome - Chancellors’ Building, room 1.12

Session 1 Regulation

CHAIR: David Leak

  • 09:00 Ciaran Condon
    • Suppression of the essential nature of RNase M16 (YqfG), required for 3' maturation of B. subtilis 16S ribosomal RNA, by deletion of RNase R
  • 09:15 Roland Hartmann
    • Function and regulation of two 6S RNAs in Bacillus subtilis
  • 09:30 Matthias Mack
    • A dual control mechanism synchronizes riboflavin and sulphur metabolism in Bacillus subtilis
  • 09:45 Hermann Rath
    • A SigB-dependent antisense RNA affects osmotic induction of opuB expression in Bacillus subtilis
  • 10:00 Laura Teichmann
    • Suppressor analysis illuminates the structure/function relationship of the glycine betaine synthesis repressor GbsR
  • 10:15 Sylvain Durand
    • sRNA-mediated activation of gene expression by inhibition of 5’-3’exonucleolytic mRNA degradation

10:30 – 11:00 Tea and Coffee - Chancellors’ Building, ground floor foyer

Session 2 Cell division

CHAIR: TBA

  • 11:00 Henrik Strahl
    • Bacillus subtilis does not form microscopically detectable cardiolipin domains
  • 11:15 Jeanine Rismondo
    • Discovery of genes required for lipoteichoic acid glycosylation predicts two distinct mechanism for wall teichoic acid glycosylation
  • 11:30 Edward de Koning
    • Divisome maturation in Bacillus subtilis single cells
  • 11:45 Seamus Holden
  • 12:00 Dirk-Jan Scheffers
  • 12:15 Yongqiang Gao
    • Cell division in the cell wall-less bacterium Acholeplasma laidlawii


12:30 – 14:30 Lunch and Poster Session 1

Session 3 – Interesting Biology

CHAIR: Colin Harwood

  • 14:30 Jörg Stülke
    • DNA topoisomerases in Bacillus subtilis: A tale on mutants and suppressors
  • 14:45 Hannah Gaimster
    • Lethal depletion of essential cell envelope proteins can be rescued by slowing DNA replication in Bacillus subtilis
  • 15:00 Alexandre Deloupy
    • Stochastic gene expression in Bacillus subtilis
  • 15:15 Sabine Schneider
    • Development of a reporter gene system to characterise riboswitch function and to identify riboswitch modulators by high-throughput screening
  • 15:30 Ken-ichi Yoshida
    • Rapid conjugative mobilization of a 100 kb segment of Bacillus subtilis chromosomal DNA is mediated by a helper plasmid with no ability for self-transfer
  • 15:45 Anna A. Toymentseva
    • Mobilization and transfer of plasmids and chromosomal DNA mediated by optimized ICEBs1 conjugative element

16:00 – 16:30 Tea and Coffee

Session 4 – Antibiotics 1

CHAIR: Ulrike Mäder

  • 16:30 Carolin Kobras
    • Exploring the substrate specificity of the antimicrobial peptide resistance transporter BceA-BceB in Bacillus subtilis
  • 16:45 Luiza P. Morawska
    • Preadaptation of Bacillus subtilis to mild osmostress contributes to increased antibiotic resistance
  • 17:00 Mary K. Phillips-Jones
    • Characterisation of the VanA-type VanS histidine kinase involved in glycopeptide resistance in Gram-positive bacteria and its ligand interactions
  • 17:15 Gabriela Henriques
    • Towards the understanding of the regulation of SppA by YteJ in Bacillus subtilis.

Free evening in Bath

Wednesday 13th June

Session 5 Biotechnology

CHAIR: Anne Breüner

  • 9:00 Andreas Knapp
    • The spacer region in the 5´-UTR strongly affects recombinant protein production in Bacillus subtilis
  • 9:15 Alexandria Holland
    • Investigating protein secretion in Geobacillus thermoglucosidasius
  • 9:30 Matthew Styles
    • Engineering Parageobacillus for the Production of Terpenes: Building Better Chassis Organisms for Industrial Biotechnology
  • 9:45 Luca Longanesi
    • γ-PGA production through Consolidated Bioprocessing in engineered B. subtilis lab strains
  • 10:00 Matteo Cavaletti
    • Optimization of γ-PGA biosynthesis supported by synthetic biology and metabolic engineering strategies
  • 10:15 Ioannis Mougiakos
    • Characterizing a thermostable Cas9 for bacterial genome editing and silencing

10:15 - 10:45 Tea and Coffee

Session 6 - Sporulation and development

CHAIR: TBC

  • 10:45 Imrich Barák
    • What we (don’t) know about the asymmetric septum in Bacillus subtilis
  • 11:00 Munehiro Asally
  • 11:15 Ilka Bischofs
    • Phenotypic memory links different stages of the B. subtilis life cycle
  • 11:30 Akos Kovacs
    • Cheating promotes evolution of hyper-cooperators by shifting phenotypic heterogeneity in biofilms
  • 11:45 Sven Halbedel
    • Novel gpsB suppressor genes contributing to regulatory proteolysis and cell division
  • 12:00 Sofia Arnaouteli
  • 12:15 Karin Bjerre
    • Investigating of Bacillus subtilis and Bacillus amyloliquefaciens spores and vegetative cells in fecal samples from pigs

12:30 – 14:30 Lunch and Poster Session 2

Session 7 – Antibiotics 2

CHAIR: Kevin Devine

  • 14:30 Auke J. van Heel
    • BAGEL4: A user-friendly web server to mine RiPPs and bacteriocins
  • 14:45 Amanda Y. van Tilburg
    • Bacillus subtilis as heterologous production host for lantibiotics
  • 15:00 Nina Lautenschlaeger
    • A novel heterologous whole-cell biosensor in Bacillus subtilis for the comprehensive detection of b-lactam antibiotics
  • 15:15 Marjorie Gibbon
    • Towards understanding signalling between the bacitracin resistance transporter BceA-BceB and histidine kinase BceS of Bacillus subtilis

15:30 – 16:00 Tea and Coffee

Session 8 – Cereus Group

CHAIR: Cinzia Calvio

  • 16:00 Monika Ehling-Schulz
    • Bacillus cereus, a multifaceted pathogen: The challenge of discriminating high and low enteropathogenic strains
  • 16:15 Nick Waterfield
    • Bacillus cereus G9241 – to anthrax and back again
  • 16:30 Ludivine Rousset
    • Oligotrophy induces phenotypic diversification of Bacillus cereus AH187
  • 16:45 Jan Maarten van Dijl
    • Can Bacillus thuringiensis and other microorganisms isolated from chronic wounds ‘pacify’ Staphylococcus aureus?

17:00 Closing Remarks

19:00 – 23:00 Social event at The Terrace, The Roman Baths, generously supported by BACIP – to include the prize giving for best posters and talks from PhD/Postdocs

END OF MEETING

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