Difference between revisions of "RapI"

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* '''Description:''' [[response regulator aspartate phosphatase]], antagonist of [[ImmR]] <br/><br/>
 
 
 
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Revision as of 12:40, 9 August 2012

Gene name rapI
Synonyms yddL
Essential no
Product response regulator aspartate phosphatase
Function control of transfer of the mobile
genetic element ICEBs1
Gene expression levels in SubtiExpress: rapI
Interactions involving this protein in SubtInteract: RapI
MW, pI 46 kDa, 5.054
Gene length, protein length 1173 bp, 391 aa
Immediate neighbours yddK, phrI
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
RapI context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
RapI expression.png
























Categories containing this gene/protein

protein modification, transcription factors and their control, quorum sensing, mobile genetic elements

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU05010

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: binds ImmR and inhibits its activity, this results in induction of the genes for the transfer of the mobile genetic element ICEBs1 PubMed
  • Protein family: RAP family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity: binding of PhrI indicates that neighbour cells do already contain the genetic element ICEBs1, this results in inactivation of RapI PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Jennifer M Auchtung, Catherine A Lee, Katherine L Garrison, Alan D Grossman
Identification and characterization of the immunity repressor (ImmR) that controls the mobile genetic element ICEBs1 of Bacillus subtilis.
Mol Microbiol: 2007, 64(6);1515-28
[PubMed:17511812] [WorldCat.org] [DOI] (P p)

R S McQuade, N Comella, A D Grossman
Control of a family of phosphatase regulatory genes (phr) by the alternate sigma factor sigma-H of Bacillus subtilis.
J Bacteriol: 2001, 183(16);4905-9
[PubMed:11466295] [WorldCat.org] [DOI] (P p)