Difference between revisions of "RapK"

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* '''Description:''' response regulator aspartate phosphatase <br/><br/>
+
* '''Description:''' response regulator aspartate phosphatase, controls [[ComA]] activity <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Product''' || response regulator aspartate phosphatase
 
|style="background:#ABCDEF;" align="center"| '''Product''' || response regulator aspartate phosphatase
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || control of sporulation initiation
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|style="background:#ABCDEF;" align="center"|'''Function''' || control of [[ComA]] activity
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 43 kDa, 5.06   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 43 kDa, 5.06   
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=== Basic information/ Evolution ===
 
=== Basic information/ Evolution ===
  
* '''Catalyzed reaction/ biological activity:'''  
+
* '''Catalyzed reaction/ biological activity:''' control of [[ComA]] activity {{PubMed|16816200}}
  
 
* '''Protein family:'''
 
* '''Protein family:'''
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* '''Cofactor(s):'''
 
* '''Cofactor(s):'''
  
* '''Effectors of protein activity:'''
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* '''Effectors of protein activity:''' binding of [[PhrK]] inhibits RapK activity {{PubMed|16816200}}
  
* '''Interactions:'''
+
* '''Interactions:''' [[RapK]]-[[PhrK]] {{PubMed|16816200}}
  
 
* '''Localization:'''
 
* '''Localization:'''
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=References=
 
=References=
<pubmed> 11466295 </pubmed>
+
<pubmed> 11466295 16816200</pubmed>
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 12:12, 29 November 2009

  • Description: response regulator aspartate phosphatase, controls ComA activity

Gene name rapK
Synonyms yobG
Essential no
Product response regulator aspartate phosphatase
Function control of ComA activity
MW, pI 43 kDa, 5.06
Gene length, protein length 1113 bp, 371 aa
Immediate neighbours yozJ, phrK
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
RapK context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU18910

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: control of ComA activity PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity: binding of PhrK inhibits RapK activity PubMed
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Jennifer M Auchtung, Catherine A Lee, Alan D Grossman
Modulation of the ComA-dependent quorum response in Bacillus subtilis by multiple Rap proteins and Phr peptides.
J Bacteriol: 2006, 188(14);5273-85
[PubMed:16816200] [WorldCat.org] [DOI] (P p)

R S McQuade, N Comella, A D Grossman
Control of a family of phosphatase regulatory genes (phr) by the alternate sigma factor sigma-H of Bacillus subtilis.
J Bacteriol: 2001, 183(16);4905-9
[PubMed:11466295] [WorldCat.org] [DOI] (P p)