RocR

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  • Description: transcriptional activator of arginine utilization operons

Gene name rocR
Synonyms
Essential no
Product transcriptional regulator
Function transcriptional activator of arginine utilization operons
MW, pI 52.6 kDa, 6.08
Gene length, protein length 1383 bp, 461 amino acids
Immediate neighbours rocD, yyxA
Gene sequence (+200bp) Protein sequence
Genetic context
File:GenE context.gif












The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: transcription activation at SigL-dependent promoters of rocABC, rocDEF, and rocG
  • Protein family: Sigma-54 interacting transcription activator
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
    • Sigma-54 factor interaction domain (143 – 372)
    • nucleotid-binding domain (171 – 178)
    • nucleotid-binding Domain (233 – 242)
    • HTH motif (434 – 453)
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions: RocR-SigL
  • Localization:

Database entries

  • Structure:
  • Swiss prot entry: [3]
  • KEGG entry: [4]
  • E.C. number:

Additional information

Expression and regulation

  • Operon: rocR
  • Regulation: autoregulation by RocR
  • Regulatory mechanism: autorepression
  • Additional information:

Biological materials

Labs working on this gene/protein

Michel Debarbouille, Pasteur Institute, Paris, FranceHomepage

Your additional remarks

References

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed