Difference between revisions of "S-box Element"

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(Genes controlled by a S-box)
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* Upon binding of SAM, the [[riboswitch]] adopts a terminator structure resulting in transcription termination.
 
* Upon binding of SAM, the [[riboswitch]] adopts a terminator structure resulting in transcription termination.
 
* In the aabsence of SAM, the [[riboswitch]] has the antitermination structure that allows transcription elongation into the controlled gene/ operon.
 
* In the aabsence of SAM, the [[riboswitch]] has the antitermination structure that allows transcription elongation into the controlled gene/ operon.
 +
* S-box riboswitch turnover is initiated by [[rny |RNase Y]]  {{PubMed|19779461}}
  
 
==Genes controlled by a S-box==
 
==Genes controlled by a S-box==
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==References==
 
==References==
  
<pubmed> 18039762,12626738 ,17381302 </pubmed>
+
<pubmed> 18039762,12626738 ,17381302 19779461 </pubmed>

Revision as of 14:40, 5 October 2009

The S-box element is a riboswitch that controls different genes of sulphur metabolism in response to the presence of S-adenosylmethionine.

  • Upon binding of SAM, the riboswitch adopts a terminator structure resulting in transcription termination.
  • In the aabsence of SAM, the riboswitch has the antitermination structure that allows transcription elongation into the controlled gene/ operon.
  • S-box riboswitch turnover is initiated by RNase Y PubMed

Genes controlled by a S-box

References

Karen Shahbabian, Ailar Jamalli, Léna Zig, Harald Putzer
RNase Y, a novel endoribonuclease, initiates riboswitch turnover in Bacillus subtilis.
EMBO J: 2009, 28(22);3523-33
[PubMed:19779461] [WorldCat.org] [DOI] (I p)

Jerneja Tomsic, Brooke A McDaniel, Frank J Grundy, Tina M Henkin
Natural variability in S-adenosylmethionine (SAM)-dependent riboswitches: S-box elements in bacillus subtilis exhibit differential sensitivity to SAM In vivo and in vitro.
J Bacteriol: 2008, 190(3);823-33
[PubMed:18039762] [WorldCat.org] [DOI] (I p)

T M Henkin, F J Grundy
Sensing metabolic signals with nascent RNA transcripts: the T box and S box riboswitches as paradigms.
Cold Spring Harb Symp Quant Biol: 2006, 71;231-7
[PubMed:17381302] [WorldCat.org] [DOI] (P p)

Brooke A Murphy McDaniel, Frank J Grundy, Irina Artsimovitch, Tina M Henkin
Transcription termination control of the S box system: direct measurement of S-adenosylmethionine by the leader RNA.
Proc Natl Acad Sci U S A: 2003, 100(6);3083-8
[PubMed:12626738] [WorldCat.org] [DOI] (P p)