SirA

• Description: unknown
  
  

Gene name	yneE or sirA
Synonyms	yoxF
Essential	no
Product	unknown
Function	unknown
MW, pI	17 kDa, 7.353
Gene length, protein length	444 bp, 148 aa
Immediate neighbours	tkt, yneF
Gene sequence (+200bp)	Protein sequence
Genetic context This image was kindly provided by SubtiList

The gene

yneE was renamed to sirA.

Basic information

• Coordinates:

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• Swiss prot entry:

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Your additional remarks

sirA (sporulation inhibitor of replication) is activated by Spo0A~P and inhibits DNA replication during sporulation.

References

PMID 19329632

1. Rahn-Lee L, Gorbatyuk B, Skovgaard O & Losick R.(2009) The Conserved Sporulation Protein YneE inhibits DNA replication in Bacillus subtilis J Bact. volume: page-page. 19329632