Difference between revisions of "Universally conserved proteins"

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'''These proteins are present in all genomes sequenced so far, from archaea and bacteria to man. So, one can say, that there is no life on earth without this small set of proteins. The genes encoding these proteins are usually essential.'''
 
'''These proteins are present in all genomes sequenced so far, from archaea and bacteria to man. So, one can say, that there is no life on earth without this small set of proteins. The genes encoding these proteins are usually essential.'''
  
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==Glycolytic enzymes==
 
==Glycolytic enzymes==
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[[ArgS]], [[PheS]], [[GltX]]
 
[[ArgS]], [[PheS]], [[GltX]]
  
==Degradation of glycoproteins==
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==tRNA modification==
* [[Gcp]] sialo-glycoprotein endopeptidase
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* [[TsaE]] tRNA modification enzyme
  
 
==Note==
 
==Note==
 
[[FtsZ]] has long been considered to be universally conserved. However, recently some ''Mycoplasma'' species lacking [[FtsZ]] have been found.
 
[[FtsZ]] has long been considered to be universally conserved. However, recently some ''Mycoplasma'' species lacking [[FtsZ]] have been found.
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==Important publications==
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<pubmed> 15479782 </pubmed>
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=Back to [[categories]]=

Latest revision as of 15:29, 18 October 2012

These proteins are present in all genomes sequenced so far, from archaea and bacteria to man. So, one can say, that there is no life on earth without this small set of proteins. The genes encoding these proteins are usually essential.

Parent category
Neighbouring categories
Related categories

none









Glycolytic enzymes

  • Eno enolase
  • Pgk phosphoglycerate kinase

Ribosomal proteins

RplA, RplB, RplC, RplE, RplF, RplK, RplN, RplR, RplV, RpsB, RpsC, RpsD, RpsE, RpsG, RpsH, RpsJ, RpsM, RpsQ, RpsS

Cellular processes

Nucleotide metabolism

  • Prs phosphoribosyl-PP-synthetase
  • Apt adenine phosphoribosyltransferase
  • TruA pseudouridylate synthase

Aminoacyl tRNA synthetases

ArgS, PheS, GltX

tRNA modification

  • TsaE tRNA modification enzyme

Note

FtsZ has long been considered to be universally conserved. However, recently some Mycoplasma species lacking FtsZ have been found.

Important publications

Michael Y Galperin, Eugene V Koonin
'Conserved hypothetical' proteins: prioritization of targets for experimental study.
Nucleic Acids Res: 2004, 32(18);5452-63
[PubMed:15479782] [WorldCat.org] [DOI] (I e)


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