YbdK

From SubtiWiki
Revision as of 10:21, 29 December 2009 by Jstuelk (talk | contribs) (References)
Jump to: navigation, search
Gene name ybdK
Synonyms
Essential no
Product two-component sensor kinase
Function unknown
MW, pI 37 kDa, 5.212
Gene length, protein length 960 bp, 320 aa
Immediate neighbours ybdJ, ybdL
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YbdK context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU02010

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: autophosphorylation, phosphorylation of YbdJ
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains: two transmembrane segments, C-terminal histidine phosphotransferase domain
  • Modification: autophosphorylation on a His residue
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization: cell membrane (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism: ComK: positive regulation PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Young Pil Kim, Kwon Joo Yeo, Myung Hee Kim, Young-Chang Kim, Young Ho Jeon
Structural characterization of the intra-membrane histidine kinase YbdK from Bacillus subtilis in DPC micelles.
Biochem Biophys Res Commun: 2010, 391(3);1506-11
[PubMed:20035725] [WorldCat.org] [DOI] (I p)

Mitsuo Ogura, Hirotake Yamaguchi, Kazuo Kobayashi, Naotake Ogasawara, Yasutaro Fujita, Teruo Tanaka
Whole-genome analysis of genes regulated by the Bacillus subtilis competence transcription factor ComK.
J Bacteriol: 2002, 184(9);2344-51
[PubMed:11948146] [WorldCat.org] [DOI] (P p)

C Fabret, V A Feher, J A Hoch
Two-component signal transduction in Bacillus subtilis: how one organism sees its world.
J Bacteriol: 1999, 181(7);1975-83
[PubMed:10094672] [WorldCat.org] [DOI] (P p)