YclK

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Gene name yclK
Synonyms
Essential no
Product two-component sensor kinase
Function unknown
Gene expression levels in SubtiExpress: yclK
Interactions involving this protein in SubtInteract: YclK
MW, pI 54 kDa, 6.152
Gene length, protein length 1419 bp, 473 aa
Immediate neighbours yclJ, rapC
Sequences Protein DNA DNA_with_flanks
Genetic context
YclK context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YclK expression.png
























Categories containing this gene/protein

protein modification, transcription factors and their control, membrane proteins, phosphoproteins

This gene is a member of the following regulons

ResD regulon

The gene

Basic information

  • Locus tag: BSU03760

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: autophosphorylation, phosphorylation of YclJ
  • Protein family:

Extended information on the protein

  • Kinetic information:
  • Domains: two transmembrane segments, C-terminal histidine phosphotransferase domain
  • Modification: autophosphorylation on a His residue
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
    • expressed under anaerobic conditions (ResD) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Elisabeth Härtig, Hao Geng, Anja Hartmann, Angela Hubacek, Richard Münch, Rick W Ye, Dieter Jahn, Michiko M Nakano
Bacillus subtilis ResD induces expression of the potential regulatory genes yclJK upon oxygen limitation.
J Bacteriol: 2004, 186(19);6477-84
[PubMed:15375128] [WorldCat.org] [DOI] (P p)

C Fabret, V A Feher, J A Hoch
Two-component signal transduction in Bacillus subtilis: how one organism sees its world.
J Bacteriol: 1999, 181(7);1975-83
[PubMed:10094672] [WorldCat.org] [DOI] (P p)