YflG

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  • Description: methionine aminopeptidase

Gene name yflG
Synonyms
Essential no
Product methionine aminopeptidase
Function removal of N-terminal methionine from nascent proteins
MW, pI 27 kDa, 5.578
Gene length, protein length 747 bp, 249 aa
Immediate neighbours yflH, nagP
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YflG context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU07690

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides (according to Swiss-Prot)
  • Protein family: peptidase M24A family (according to Swiss-Prot)
  • Paralogous protein(s): Map

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
    • YvoA: transcription repression (weak and not certain) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

CongHui You, HongYan Lu, Agnieszka Sekowska, Gang Fang, YiPing Wang, Anne-Marie Gilles, Antoine Danchin
The two authentic methionine aminopeptidase genes are differentially expressed in Bacillus subtilis.
BMC Microbiol: 2005, 5;57
[PubMed:16207374] [WorldCat.org] [DOI] (I e)