Difference between revisions of "YodB"

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==Reviews==
 
==Reviews==
<pubmed>20626317</pubmed>
+
 +
Antelmann H, Helmann JD.
 +
Thiol-based redox switches and gene regulation.
 +
Antioxid Redox Signal. 2011,14:1049-63.
 +
{{PubMed|20626317}}
 +
 
 +
<pubmed>18282125</pubmed>
  
 
==Original Publications==
 
==Original Publications==

Revision as of 19:56, 16 January 2012

  • Description: MarR/DUF24-family transcription repressor of azoR1, catD-catE and yodC expression

Gene name yodB
Synonyms
Essential no
Product MarR/DUF24-family transcription repressor
Function regulation of quinone and diamide detoxification
MW, pI 12 kDa, 4.737
Gene length, protein length 336 bp, 112 aa
Immediate neighbours yodA, yodC
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YodB context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

transcription factors and their control, resistance against oxidative and electrophile stress

This gene is a member of the following regulons

YodB regulon

The YodB regulon:

The gene

Basic information

  • Locus tag: BSU19540

Phenotypes of a mutant

increased resistance to catechol, quinones and diamide PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: MarR/DUF24-family
  • Paralogous protein(s): CatR

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification: redox-controlled by intersubunit disulfide formation of Cys6 and Cys101' in response to quinones and diamide
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
    • subject to autorepression PubMed
  • Regulatory mechanism:
    • YodB: transcription repression PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Haike Antelmann,University of Greifswald, Germany

Your additional remarks

References

Reviews

Antelmann H, Helmann JD.
Thiol-based redox switches and gene regulation.
Antioxid Redox Signal. 2011,14:1049-63.
PubMed

Haike Antelmann, Michael Hecker, Peter Zuber
Proteomic signatures uncover thiol-specific electrophile resistance mechanisms in Bacillus subtilis.
Expert Rev Proteomics: 2008, 5(1);77-90
[PubMed:18282125] [WorldCat.org] [DOI] (I p)


Original Publications