Difference between revisions of "YvrG"

From SubtiWiki
Jump to: navigation, search
Line 37: Line 37:
 
=== Basic information ===
 
=== Basic information ===
  
* '''Locus tag:'''
+
* '''Locus tag:''' BSU33210
  
 
===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
Line 84: Line 84:
 
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/O34989 O34989]
 
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/O34989 O34989]
  
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU33210 BSU33210]
+
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU33210]
  
 
* '''E.C. number:'''
 
* '''E.C. number:'''

Revision as of 11:08, 3 June 2009

  • Description: sensor kinase of the YvrG-YvrHb two-component system

Gene name yvrG
Synonyms
Essential no
Product two-component sensor histidine kinase
Function regulation cell surface maintenance
MW, pI 66 kDa, 9.518
Gene length, protein length 1719 bp, 573 aa
Immediate neighbours yvrE, yvrHb
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YvrG context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU33210

Phenotypes of a mutant

unusual autolysis and higher susceptibility to cell envelope antibiotics (bacitracin, aztreonam, cefepime, fosfomycin) PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: ATP + protein L-histidine = ADP + protein N-phospho-L-histidine (according to Swiss-Prot) phosphorylation of the YvrHb response regulator PubMed
  • Protein family:

Extended information on the protein

  • Kinetic information:
  • Domains: two transmembrane segments, C-terminal histidine phosphotransferase domain
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization: cell membrane (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Serizawa M, Kodama K, Yamamoto H, Kobayashi K, Ogasawara N, Sekiguchi J. (2005) Functional analysis of the YvrGHb two-component system of Bacillus subtilis: identification of the regulated genes by DNA microarray and northern blot analyses. Biosci. Biotechnol. Biochem. 69: 2155-2169. PubMed
  2. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed