gntR

168

transcriptional repressor (GntR family) of the gntR-gntK-gntP-gntZ operon

locus: BSU_40050

Molecular weight: 28.13 kDa

pI: 5.26

Protein length: 243 aa

Gene length: 732 bp

function: regulation of gluconate utilization

product: transcriptional repressor of the gluconate operon

essential: no

synonyms: gntR

List of homologs in different organisms, belongs to COG1802 (Galperin et al., 2021)

Gene

Coordinates: 4,113,417  4,114,148

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The protein

Protein family

• [wiki|GntR family] of transcription factors

[wiki|Domains]

• [wiki|HTH gntR-type domain] (aa 17-83) (according to UniProt)

Structure

• [AF|P10585]

Effectors of protein activity

• gluconate acts as molecular inducer

Biological materials

Mutant

• BKE40050 ([gene|1C566E54F8EF1A17A365FC49DFDA452AC5D0CA64|gntR]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE40050 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATACACTCACCTTCCTCAC,  downstream forward: _UP4_CTGGCAAAAGGAGCTGAATA
• BKK40050 ([gene|1C566E54F8EF1A17A365FC49DFDA452AC5D0CA64|gntR]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK40050 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATACACTCACCTTCCTCAC,  downstream forward: _UP4_CTGGCAAAAGGAGCTGAATA

References

• 8370661,8808939,8288545,7642511,7476858,8596444,3011959,2163901,3037520,2492998,9106211,2419835,2124676,3020045,10746760,8510140,2843515,7476858,3020045,1659648,21106498,22900538,220817675,27829583