pucR

pucR
168

transcriptional regulator of puc genes

locus
BSU_32420
Molecular weight
60.34 kDa
pI
6.19
Protein length
Gene length
function
regulation of purine utilization
product
transcriptional regulator of puc genes ([wiki|PucR family])
essential
no
synonyms
pucR, yunI

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2508 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,328,762  3,330,357
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The protein
Protein family
[wiki|PucR family]
[wiki|CdaR family] (according to UniProt)
Structure
[AF|O32138]
Expression and Regulation
Operons
genes
[gene|52C1601482C26400A524E880334BB801F832D6ED|pucR]-[gene|53950BFDC128DE46F3F43BDB9D0FDB3D645152DF|pucJ]-[gene|3162EF36F4441A1E4EBBFDAD19F6768D8EF21B29|pucK]-[gene|2E7DEC53A130247E66225E87950D702E462C324F|pucL]-[gene|A2F93FFE225DFDBCBB3EA079BEF84C79465F0E5C|pucM]
description
[Pubmed|12823818]
regulation
expressed in the absence of good nitrogen sources (glutamine or ammonium) ([protein|search|TnrA]) [Pubmed|12823818]
regulatory mechanism
[protein|52C1601482C26400A524E880334BB801F832D6ED|pucR]: auto-repression, [Pubmed|12029039], in [regulon|protein:52C1601482C26400A524E880334BB801F832D6ED|pucR regulon]
[protein|857EF1AC54DEA0690C01B7F8CEFFD16312C58F20|tnrA]: activation, [Pubmed|25755103], in [regulon|protein:857EF1AC54DEA0690C01B7F8CEFFD16312C58F20|tnrA regulon]
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[gene|52C1601482C26400A524E880334BB801F832D6ED|pucR]→[gene|A2F93FFE225DFDBCBB3EA079BEF84C79465F0E5C|pucM]

2024-02-29 20:40:45

ghost

63

276c5386b42b4339a3f84f40bd6b93a74b30984d

76659AC9EBD93756B8415A24C45B3DC60C799944

Biological materials
Mutant
MGNA-A934 (yunI::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/934 NBRP B. subtilis, Japan]
BKE32420 ([gene|52C1601482C26400A524E880334BB801F832D6ED|pucR]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE32420 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATAGCGCATTCTCCTTTTC,  downstream forward: _UP4_TAAAGTTTGTTACATTTTCT
BKK32420 ([gene|52C1601482C26400A524E880334BB801F832D6ED|pucR]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK32420 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATAGCGCATTCTCCTTTTC,  downstream forward: _UP4_TAAAGTTTGTTACATTTTCT
References
12374841,11344136,12029039,12823818,25755103

52C1601482C26400A524E880334BB801F832D6ED

Page visits: 5485

Time of last update: 2024-03-28 06:36:00

Author of last update: Melvin.boenninger