SepF - Revision history

Jstuelk at 12:43, 22 May 2014

2014-05-22T12:43:53Z

134.76.70.252 at 09:34, 17 April 2014

2014-04-17T09:34:17Z

134.76.38.147 at 13:40, 2 April 2014

2014-04-02T13:40:07Z

Jstuelk at 10:33, 15 December 2013

2013-12-15T10:33:11Z

134.76.70.252 at 14:16, 18 November 2013

2013-11-18T14:16:29Z

Jstuelk at 16:53, 13 November 2013

2013-11-13T16:53:27Z

134.76.70.252 at 13:17, 16 May 2013

2013-05-16T13:17:19Z

134.76.70.252 at 10:10, 14 May 2013

2013-05-14T10:10:17Z

134.76.70.252 at 12:46, 13 May 2013

2013-05-13T12:46:46Z

Jstuelk: /* Original Publications */

2012-08-23T11:54:32Z

‎Original Publications

@@ Line 123: / Line 123: @@
 * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=sepF_1610865_1611314_1 sepF] {{PubMed|22383849}}
-* '''Sigma factor:'''
+* '''[[Sigma factor]]:'''
 * '''Regulation:'''
@@ Line 137: / Line 137: @@
 =Biological materials =
 * '''Mutant:'''
 * '''Expression vector:'''

← Older revision		Revision as of 09:34, 17 April 2014
Line 132:		Line 132:

	* '''Additional information:'''		* '''Additional information:'''
		+	** number of protein molecules per cell (minimal medium with glucose and ammonium): 437 {{PubMed\|24696501}}
		+	** number of protein molecules per cell (complex medium with amino acids, without glucose): 837 {{PubMed\|24696501}}

	=Biological materials =		=Biological materials =

@@ Line 61: / Line 61: @@
 === Database entries ===
 * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/ylmDEFGH.html]
@@ Line 103: / Line 104: @@
 === Database entries ===
 * '''Structure:'''

@@ Line 1: / Line 1: @@
-* '''Description:''' part of the divisome, recruits [[FtsZ]] to the membrane <br/><br/>
+* '''Description:''' part of the [[divisome]], recruits [[FtsZ]] to the membrane <br/><br/>
 {| align="right" border="1" cellpadding="2"
@@ Line 58: / Line 58: @@
 * less efficient cell division results in longer cells. Electron microscopy reveals strongly distorted division septa.
 * the ''[[sepF]]'' mutation in combination with a constitutively active form of [[WalR]] ([[WalR]]-R204C) results in the formation of cell wall-less L-forms {{PubMed|22122227}}
-* the ''sepF'' mutation is synthetically lethal in combination with an ''[[ezrA]]'' mutation or an ''[[ftsA]]'' mutation
+* the ''sepF'' mutation is synthetically lethal in combination with an ''[[ezrA]]'' mutation or an ''[[ftsA]]'' mutation {{PubMed|24218584}}
 === Database entries ===
@@ Line 74: / Line 74: @@
 * '''Catalyzed reaction/ biological activity:'''
 ** SepF assembles into very large (∼50 nm diameter) rings. These rings are able to bundle [[FtsZ]] protofilaments into strikingly long and regular tubular structures reminiscent of eukaryotic microtubules {{PubMed|21224850}}
 * '''Protein family:''' sepF family (according to Swiss-Prot)
@@ Line 83: / Line 84: @@
 * '''Kinetic information:'''
-* '''Domains:'''
+* '''[[Domains]]:'''
 ** N-terminal amphipatic helix for membrane binding {{PubMed|24218584}}
-** C-terminal [[FtsZ]]-binding domain {{PubMed|24218584}}
+** C-terminal globular [[FtsZ]]-binding domain {{PubMed|24218584}}
 * '''Modification:'''
-* '''Cofactor(s):'''
+* '''[[Cofactors]]:'''
 * '''Effectors of protein activity:'''
 * '''[[SubtInteract|Interactions]]:'''
 ** [[FtsZ]] (extreme C terminus of [[FtsZ]])-[[SepF]] {{PubMed|24218584,22912848,16420366}}

@@ Line 16: / Line 16: @@
 |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU15390 sepF]
 |-
-|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/SepF SepF]
+|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=SepF SepF]
 |-
 |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 17 kDa, 4.863

@@ Line 1: / Line 1: @@
-* '''Description:''' part of the divisome <br/><br/>
+* '''Description:''' part of the divisome, recruits [[FtsZ]] to the membrane <br/><br/>
 {| align="right" border="1" cellpadding="2"
@@ Line 12: / Line 12: @@
 |style="background:#ABCDEF;" align="center"| '''Product''' || [[FtsZ]]-interacting protein
 |-
-|style="background:#ABCDEF;" align="center"|'''Function''' || proper execution of septum synthesis
+|style="background:#ABCDEF;" align="center"|'''Function''' || recruitment of [[FtsZ]]
 |-
 |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU15390 sepF]
@@ Line 39: / Line 39: @@
 <br/><br/><br/><br/>
 <br/><br/><br/><br/>
-<br/><br/><br/><br/>
+<br/><br/>
 = [[Categories]] containing this gene/protein =
-{{SubtiWiki category|[[cell division]]}}
+{{SubtiWiki category|[[cell division]]}},
 = This gene is a member of the following [[regulons]] =
@@ Line 57: / Line 58: @@
 * less efficient cell division results in longer cells. Electron microscopy reveals strongly distorted division septa.
 * the ''[[sepF]]'' mutation in combination with a constitutively active form of [[WalR]] ([[WalR]]-R204C) results in the formation of cell wall-less L-forms {{PubMed|22122227}}
 === Database entries ===
@@ Line 82: / Line 84: @@
 * '''Domains:'''
 * '''Modification:'''
@@ Line 90: / Line 94: @@
 * '''[[SubtInteract|Interactions]]:'''
-** [[FtsZ]] (extreme C terminus of [[FtsZ]])-[[SepF]] {{PubMed|22912848,16420366}}
+** [[FtsZ]] (extreme C terminus of [[FtsZ]])-[[SepF]] {{PubMed|24218584,22912848,16420366}}
-* '''[[Localization]]:''' septum {{PubMed|16420366}}
+* '''[[Localization]]:'''
 === Database entries ===
 * '''Structure:'''
 * '''UniProt:''' [http://www.uniprot.org/uniprot/O31728 O31728]
@@ Line 150: / Line 157: @@
 ==Original Publications==
-'''Additional publications:''' {{PubMed|22912848,21224850,22122227}}
+<pubmed>16420366,16796675,14651647, 24218584 22912848,21224850,22122227</pubmed>
 [[Category:Protein-coding genes]]

@@ Line 31: / Line 31: @@
   <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 |-
-|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=sepF_1610865_1611314_1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:sepF_expression.png|500px]]
+|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=sepF_1610865_1611314_1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:sepF_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU15390]]
 |-
 |}

@@ Line 24: / Line 24: @@
 |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ylmE]]'', ''[[ylmG]]''
 |-
-|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU15390 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU15390 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU15390 Advanced_DNA]
+|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU15390 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU15390 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU15390 DNA_with_flanks]
 |-
 |-

@@ Line 150: / Line 150: @@
 ==Original Publications==
-'''Additional publications:''' {{PubMed|21224850,22122227}}
+'''Additional publications:''' {{PubMed|22912848,21224850,22122227}}
-<pubmed>16420366,16796675,14651647, 22912848</pubmed>
+<pubmed>16420366,16796675,14651647,</pubmed>
 [[Category:Protein-coding genes]]