Difference between revisions of "MutY"
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|style="background:#ABCDEF;" align="center"|'''Function''' || DNA repair  | |style="background:#ABCDEF;" align="center"|'''Function''' || DNA repair  | ||
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| + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU08630 mutY]  | ||
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/fatty_acid_synthesis.html Lipid synthesis]'''  | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/fatty_acid_synthesis.html Lipid synthesis]'''  | ||
Revision as of 16:07, 6 August 2012
| Gene name | mutY | 
| Synonyms | yfhQ | 
| Essential | no | 
| Product | A/G-specific adenine glycosylase | 
| Function | DNA repair | 
| Gene expression levels in SubtiExpress: mutY | |
|  Metabolic function and regulation of this protein in SubtiPathways:  Lipid synthesis  | |
| MW, pI | 41 kDa, 6.044 | 
| Gene length, protein length | 1107 bp, 369 aa | 
| Immediate neighbours | yfhP, yfhS | 
| Get the DNA and protein sequences  (Barbe et al., 2009)  | |
 Genetic context  
  This image was kindly provided by SubtiList 
 | |
Expression at a glance   PubMed 
 | |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU08630
 
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
 
- SubtiList entry: [2]
 
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: releases adenines from 8-oxo-G:A mismatches
 
- Protein family:
 
- Paralogous protein(s):
 
Extended information on the protein
- Kinetic information:
 
- Domains:
 
- Modification:
 
- Cofactor(s):
 
- Effectors of protein activity:
 
Database entries
- Structure: 1RRS (complex with DNA, Geobacillus stearothermophilus)
 
- UniProt: O31584
 
- KEGG entry: [3]
 
- E.C. number:
 
Additional information
Expression and regulation
- Regulation:
 
- Regulatory mechanism:
 
- Additional information:
 
Biological materials
- Mutant:
 
- Expression vector:
 
- lacZ fusion:
 
- GFP fusion:
 
- two-hybrid system:
 
- Antibody:
 
Labs working on this gene/protein
Your additional remarks
References
Luz E Vidales, Lluvia C Cárdenas, Eduardo Robleto, Ronald E Yasbin, Mario Pedraza-Reyes  
Defects in the error prevention oxidized guanine system potentiate stationary-phase mutagenesis in Bacillus subtilis. 
J Bacteriol: 2009, 191(2);506-13 
[PubMed:19011023]
  [WorldCat.org]
 [DOI]
 (I p)
Hiroki Yamamoto, Masao Mori, Junichi Sekiguchi  
Transcription of genes near the sspE locus of the Bacillus subtilis genome. 
Microbiology (Reading): 1999, 145 ( Pt 8);2171-2180 
[PubMed:10463184]
  [WorldCat.org]
 [DOI]
 (P p)
Additional publications: PubMed

