PdxT

• Description: pyridoxal-5'-phosphate synthase (glutaminase domain)
  
  

Gene name	pdxT
Synonyms	yaaE
Essential	no
Product	pyridoxal-5'-phosphate synthase (glutaminase domain)
Function	pyridoxal-5'-phosphate biosynthesis
MW, pI	21 kDa, 4.984
Gene length, protein length	588 bp, 196 aa
Immediate neighbours	pdxS, serS
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

biosynthesis of cofactors

This gene is a member of the following regulons

Spo0A regulon

The gene

Basic information

• Locus tag: BSU00120

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: glutamine amidotransferase pdxT/SNO family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: PdxS-PdxT PubMed1 PubMed2

• Localization:

Database entries

• Structure: PdxT 2NV0, PdxS-PdxT complex 2NV2

• UniProt: P37528

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: pdxS-pdxT

• Sigma factor:

• Regulation: negatively controlled by Spo0A PubMed
  • repressed under conditions that trigger sporulation (Spo0A) PubMed

• Regulatory mechanism:
  • Spo0A: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: