View source for FbpA

* '''Description:''' Fur-regulated basic protein, acts as RNA chaperone for ''[[fsrA]]'' <br/><br/>

{| align="right" border="1" cellpadding="2" 
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''fbpA''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''ydbN''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || Fur-regulated basic protein, <br/>acts as RNA chaperone for ''[[fsrA]]''
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || RNA chaperone 
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=FbpA FbpA]'''
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || xx,x kDa, 9.50 
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 159 bp, 53 amino acids
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[fbpB]]'', ''[[ydbO]]''
|-
|style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/genE_nucleotide.txt     Gene sequence      (+200bp)   ]''' 
|style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/genE_protein.txt Protein sequence]'''
|-
|colspan="2" | '''Genetic context''' <br/> [[Image:FbpA_fbpB_context.jpeg]]
|-
|colspan="2" |'''[http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=ydbN Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:ydbN_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU04530]]
|-
|}

__TOC__

<br/><br/><br/>

= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[acquisition of iron]]}},
{{SubtiWiki category|[[iron metabolism]]}},
{{SubtiWiki category|[[RNA chaperones]]}},
{{SubtiWiki category|[[short peptides]]}}

= This gene is a member of the following [[regulons]] =
{{SubtiWiki regulon|[[Fur regulon]]}}

=The gene=

=== Basic information ===

* '''Locus tag:'''

===Phenotypes of a mutant ===
* transcription profile of a ''[[fbpA]] [[fbpB]]'' double mutant strain: [http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE27416 GEO] {{PubMed|22389480}}

=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=?&redirect=T ?]
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=?&redirect=T ?]

* '''DBTBS entry:''' no entry

* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG12081]

* '''GEO entry:''' [http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE27416 GEO] {{PubMed|22389480}}

=== Additional information===

The sequence of the former ydbN gene was corrected, and does now contain two genes, [[fbpA]] and [[fbpB]]. [http://www.ncbi.nlm.nih.gov/sites/entrez/18697947 PubMed]



=The protein=

=== Basic information/ Evolution ===

* '''Catalyzed reaction/ biological activity:''' 

* '''Protein family:'''

* '''Paralogous protein(s):'''

=== Extended information on the protein ===

* '''Kinetic information:'''	

* '''Domains:''' 

* '''Modification:'''

* '''Cofactor(s):'''

* '''Effectors of protein activity:'''

* '''Interactions:'''

* '''Localization:'''

=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=?&redirect=T ?]
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=?&redirect=T ?]

* '''Structure:'''	

* '''Swiss prot entry:'''

* '''KEGG entry:''' no entry

* '''E.C. number:'''

=== Additional information===

=Expression and regulation=
* '''Operon:''' ''[[fbpA]]-[[fbpB]]'' {{PubMed|18697947}} 

* '''[[Sigma factor]]:''' 

* '''Regulation:''' 
** induced upon iron starvation ([[Fur]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/12354229 PubMed]

* '''Regulatory mechanism:''' 
** [[Fur]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/12354229 PubMed]

* '''Additional information:''' 

=Biological materials =

* '''Mutant:'''

* '''Expression vector:'''
	
* '''lacZ fusion:'''

* '''GFP fusion:'''

* '''two-hybrid system:''' 

* '''Antibody:'''

=Labs working on this gene/protein=

=Your additional remarks=

=References=

<pubmed>18697947, 22389480 </pubmed>

[[Category:short peptide]]