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Elongasome

From SubtiWiki

A protein complex that catalyzes peptidoglycan biosynthesis and is thereby involved in maintaining cell shape

Complex members

  • cell wall biosynthetic enzymes at the outer side of the membrane: penicillin-binding proteins (PbpA, PbpH, perhaps also PbpC, DacC, PbpI)
  • transmembrane proteins: MreC, MreD, RodA, RodZ, they couple the cytosolic actin-like proteins to the extracellular peptidoglycan-synthesizing machinery
  • actin-like proteins at the inner surface of the membrane: MreB, MreBH, Mbl, the polymers control/restrict the mobility of the cell wall elongation enzyme complex

Related pages

Labs working on the complex

Important publications

<pubmed>21636744 21636745 23848140 21725336 24094808 26029191</pubmed>

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