moaE

moaE
168

molybdopterin synthase (large subunit), catalyses the transfer of sulfide from MoaD thiocarboxylate

locus
BSU_14300
Molecular weight
17.64 kDa
pI
4.75
Protein length
157 aaSequenceBlast
Gene length
474 bpSequenceBlast
function
nitrate respiration
product
molybdopterin synthase (large subunit)
essential
no
ec
null
synonyms
moaE
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0314 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,498,966  1,499,439
The protein
Catalyzed reaction/ biological activity
catalyses the transfer of sulfide from [protein|5C3EAEE1287FFB1541A31B31A8B6627E60A4D2EB|moaD] thiocarboxylate
2 [molybdopterin-synthase sulfur-carrier protein]-C-terminal Gly-NH-CH2-C(O)SH + cyclic pyranopterin phosphate + H2O --> 2 [molybdopterin-synthase sulfur-carrier protein]-C-terminal Gly-Gly + 4 H+ + molybdopterin (according to UniProt)
Protein family
moaE family (single member, according to UniProt)
Structure
[PDB|1NVI] (the [protein|5C3EAEE1287FFB1541A31B31A8B6627E60A4D2EB|moaD]-[protein|12F27FA4DB8232B52271565C4F4937520A4F5C7B|moaE] complex from ''E. coli'')  [Pubmed|12571227]
[AF|O31705]
Expression and Regulation
Operons
genes
[gene|C6DB8499752ED1DBF276C0E46CC561450BED6A40|mobA]-[gene|C163CF34BAA3A37DCC67851DEE5889BB7AD208AB|moeB]-[gene|03DBD906E31D6A8A4D14C9E2DACF0F1AB9F8DAA8|moeA]-[gene|A283C34375EDF495940E2F03C4FB6A9FE841FA1E|mobB]-[gene|12F27FA4DB8232B52271565C4F4937520A4F5C7B|moaE]-[gene|5C3EAEE1287FFB1541A31B31A8B6627E60A4D2EB|moaD]
description
[Pubmed|22383849]
Open in new tab

[gene|C6DB8499752ED1DBF276C0E46CC561450BED6A40|mobA]→[gene|5C3EAEE1287FFB1541A31B31A8B6627E60A4D2EB|moaD]

2025-05-10 20:16:22

ghost

73

3e77aa073340231ecb5f4eac2f2e17e6412a023a

7774957680F4BBF86496D8670D37DCF0E162B98C

Biological materials
Mutant
BKE14300 ([gene|12F27FA4DB8232B52271565C4F4937520A4F5C7B|moaE]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE14300 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_TTTCGTAATCTCAAACCGTT,  downstream forward: _UP4_CCAGACCTAAGCGAGGGAGA
BKK14300 ([gene|12F27FA4DB8232B52271565C4F4937520A4F5C7B|moaE]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK14300 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_TTTCGTAATCTCAAACCGTT,  downstream forward: _UP4_CCAGACCTAAGCGAGGGAGA
References
Reviews
22616866,23539623
Original Publications
12571227,22383849

12F27FA4DB8232B52271565C4F4937520A4F5C7B

Page visits: 2041

Time of last update: 2025-05-18 10:01:20

Author of last update: Melvin.boenninger