ykcB
168
glucosyltransferase, transfer of glucose from C55-P-Glc to a target molecule
locus
BSU_12880
Molecular weight
76.28 kDa
pI
9.53
function
unknown
product
glucosyltransferase
essential
no
synonyms
ykcB
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1807 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,354,285 1,356,435
Phenotypes of a mutant
poorly transformable [pubmed|28189581]
reduced susceptibility to vancomycin [pubmed|36409129]
The protein
Protein family
glycosyltransferase 39 family (with [protein|CFEA05E10517C00222126F959A1D2DCE7604E478|yycA], according to UniProt)
Structure
[AF|O34575]
Paralogous protein(s)
[protein|CFEA05E10517C00222126F959A1D2DCE7604E478|yycA]
Expression and Regulation
Operons
genes
[gene|7039FCF49F97FFEF37ED48D6F860E3873A5CF308|ykcB]-[gene|FD76A781162795EAF174B59C0A90D2ED3ACC0AB7|ykcC]
description
[Pubmed|18175906]
regulatory mechanism
[protein|706983E6942E883D3A9D45693E7B4015AEABE60B|yclJ]: activation, [Pubmed|20512483], in [regulon|protein:706983E6942E883D3A9D45693E7B4015AEABE60B|yclJ regulon]
[protein|1582F9E6510C4FA87B3A5F3F4A7F39008C654AA9|yrkP]: activation, [Pubmed|18175906], in [regulon|protein:1582F9E6510C4FA87B3A5F3F4A7F39008C654AA9|yrkP regulon]
Biological materials
Mutant
MGNA-A738 (ykcB::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/738 NBRP B. subtilis, Japan]
BKE12880 ([gene|7039FCF49F97FFEF37ED48D6F860E3873A5CF308|ykcB]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE12880 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACTTATTTTTCACTCCTTT, downstream forward: _UP4_GCTGATGAATAGGAGGCAAA
BKK12880 ([gene|7039FCF49F97FFEF37ED48D6F860E3873A5CF308|ykcB]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK12880 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACTTATTTTTCACTCCTTT, downstream forward: _UP4_GCTGATGAATAGGAGGCAAA
References
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Time of last update: 2025-05-10 21:25:26
Author of last update: Jstuelk