yplP
168
transcriptional activator (for [protein|1118A21CC581B0470EC6E7C178F2523CDCA70F93|sigL]-dependent promoter)
locus
BSU_21780
Molecular weight
37.05 kDa
pI
9.3
function
required for survival at low temperatures
product
transcriptional activator (for [protein|1118A21CC581B0470EC6E7C178F2523CDCA70F93|sigL]-dependent promoter)
essential
no
synonyms
yplP
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1221 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
2,294,286 2,295,281
Phenotypes of a mutant
The mutant is cold-sensitive [http://www.ncbi.nlm.nih.gov/sites/entrez/16585774 PubMed]
The protein
Protein family
[wiki|Transcription factors activating transcription at SigL-dependent promoters]
[wiki|Domains]
[wiki|Sigma-54 factor interaction domain] (aa 12-213) (according to UniProt)
Structure
[PDB|3DZD] (Aquifex aeolicus NtrC, corresponds to aa 12 ... 333 of YplP, 33% identity) [pubmed|18955063]
[AF|P54156]
Expression and Regulation
Operons
genes
[gene|90C747D6D6194608C2CF9566F1740A6B20966A11|yplP]-[gene|8C382ECBEE4E2911E0233E0882BEA754156B9D40|trhA]
description
[Pubmed|22383849]
Biological materials
Mutant
MGNA-A896 (yplP::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/896 NBRP B. subtilis, Japan]
GP2304 ( ''yplP''::aphA3), available in [wiki|Jörg Stülke]'s lab
BKE21780 ([gene|90C747D6D6194608C2CF9566F1740A6B20966A11|yplP]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE21780 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCAATTGGCTCCTTTTGG, downstream forward: _UP4_TAGCGATCGAAAGGAGAATG
BKK21780 ([gene|90C747D6D6194608C2CF9566F1740A6B20966A11|yplP]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK21780 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCAATTGGCTCCTTTTGG, downstream forward: _UP4_TAGCGATCGAAAGGAGAATG
References
Page visits: 3434
Time of last update: 2025-05-10 12:06:27
Author of last update: Melvin.boenninger