ydfS
168
required for wet heat resistance of spores
locus
BSU_05540
Molecular weight
26.96 kDa
pI
8.45
function
stabilization of spore inner membrane proteins against wet heat
product
inner spore membrane protein
essential
no
synonyms
ydfS
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG2323 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
601,019 → 601,726
Phenotypes of a mutant
reduced wet heat resistance [pubmed|37113233]
decreased spore resistance to heat and chemicals [pubmed|40938645]
deficient in spore germination in response to AGFK [pubmed|37113233]
The protein
Protein family
[wiki|UPF0702 family] (according to UniProt)
Structure
[PDB|3C6F] ([protein|EBD0F966FD7B3662814D530064BD307561A5CB15|yetF], corresponds to aa 81 ... 230, 36% identity)
[AF|P96697]
Paralogous protein(s)
[protein|EBD0F966FD7B3662814D530064BD307561A5CB15|yetF]
[wiki|Localization]
inner spore membrane [pubmed|37113233]
Expression and Regulation
Operons
genes
[gene|B37938C639FC87DAA72AA82998DA8DF25E63CF37|ydfS]
description
[Pubmed|16497325]
regulation
expressed during sporulation in the forespore ([protein|search|SigG]) [Pubmed|16497325]
sigma factors
[protein|5F24258282F3166B7696B9E9ABC1706E4D06C944|sigG]: sigma factor, [Pubmed|16497325], in [regulon|protein:5F24258282F3166B7696B9E9ABC1706E4D06C944|sigG regulon]
Biological materials
Mutant
MGNA-C156 (ydfS::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2154 NBRP B. subtilis, Japan]
BKE05540 (Δ[gene|B37938C639FC87DAA72AA82998DA8DF25E63CF37|ydfS]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE05540 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTTATGGCGCTCCCCGC, downstream forward: _UP4_AAGGAATGAAGGAACAATCA
BKK05540 (Δ[gene|B37938C639FC87DAA72AA82998DA8DF25E63CF37|ydfS]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK05540 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTTATGGCGCTCCCCGC, downstream forward: _UP4_AAGGAATGAAGGAACAATCA
References
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Time of last update: 2025-10-23 05:09:33
Author of last update: Jstuelk